@article { ISI:000350754400004,
	title = {Target cum flexibility: synthesis of indolo[1,2-b]isoquinoline derivatives via cobalt-catalyzed [2+2+2] cyclotrimerization},
	journal = {Synlett},
	volume = {26},
	number = {5},
	year = {2015},
	month = {MAR},
	pages = {604-608},
	publisher = {GEORG THIEME VERLAG KG},
	address = {RUDIGERSTR 14, D-70469 STUTTGART, GERMANY},
	abstract = {<p>A modular approach for the synthesis of small molecules having the unnatural 6,11-dihydroindolo[1,2-b]isoquinoline tetracyclic core has been documented. An acid-catalyzed Friedel-Crafts-type C2-alkylation of N-propargyl indole with a suitably activated alkynol has been used to prepare the key indole-derived diynes. The cobalt-catalyzed [2+2+2] cyclotrimerization of these diynes has been studied with various internal/terminal alkynes and with nitriles.</p>},
	keywords = {2-b]-isoquinoline, cobalt, Indole, indolo[1, Pyridine, [2+2+2] cyclotrimerization},
	issn = {0936-5214},
	doi = {10.1055/s-0034-1379950},
	author = {Swami, Anuradha and Ramana, Chepuri V.}
}
