@article { ISI:000237886100006, title = {Convenient chemoenzymatic synthesis of (1S,7aS)-1-hydroxy-5-oxo-4-(2 {\textquoteleft}-carboxyethyl)-7a-methyltetrahydro-indane - a key intermediate of steroids}, journal = {Journal of Molecular Catalysis B-Enzymatic}, volume = {40}, number = {1-2}, year = {2006}, month = {MAY}, pages = {38-43}, publisher = {ELSEVIER SCIENCE BV}, type = {Article}, address = {PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS}, abstract = {

A porcine pancreatic lipase mediated enzymatic hydrolysis of (+/-)-1-acetoxy-5-oxo-4-(2 {\textquoteleft}-carbomethoxyethyl)-7a-methyltetrahydroindane (5b) furnished (1S,7aS)-1-acetoxy-5-oxo-4-(2 {\textquoteleft}-carbomethoxyethyl)-7a-methyltetrahydro-indane (9) and (1R,7aR)-1-hydroxy-5-oxo-4-(2 {\textquoteleft}-carbomethoxyethyl)-7a-methyltetrahydro-indane (8) with \> 99\% e.e. which on further chemical hydrolysis gave 1 and ent-1, key intermediates of steroids. (c) 2006 Elsevier B.V. All rights reserved.

}, keywords = {chemoenzymatic method, Enzymatic hydrolysis, steroids, terpenoids}, issn = {1381-1177}, doi = {10.1016/j.molcatb.2006.01.037}, author = {Kalkote, Uttam R. and Purude, A. N. and Puranik, Vedavati G. and Gurjar, M. K.} } @article { ISI:000249894100012, title = {Convenient formal synthesis of (+/-)-paroxetine}, journal = {Synthetic Communications}, volume = {37}, number = {18}, year = {2007}, month = {SEP}, pages = {3143-3149}, publisher = {TAYLOR \& FRANCIS INC}, type = {Article}, address = {325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA}, abstract = {

A formal total synthesis of antidepressant (+/-)-paroxetine employing a solvent-free Heck reaction is disclosed.

}, keywords = {antidepressants, carbamate, electrophile, Heck reaction, piperidines}, issn = {0039-7911}, doi = {10.1080/00397910701545130}, author = {Chavan, Subhash P. and Khobragade, Dushant A. and Pathak, Ashok B. and Kalkote, Uttam R.} } @article { ISI:000291139700014, title = {Convenient formal synthesis of (2S,3S)-3-hydroxy pipecolic acid}, journal = {Tetrahedron-Asymmetry}, volume = {22}, number = {5}, year = {2011}, month = {MAR}, pages = {587-590}, publisher = {PERGAMON-ELSEVIER SCIENCE LTD}, address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND}, abstract = {

A convenient synthesis of (2S,3S)-3-hydroxy pipecolic acid starting from inexpensive and easily available L-(+)-tartaric acid has been described. (C) 2011 Elsevier Ltd. All rights reserved.

}, issn = {0957-4166}, doi = {10.1016/j.tetasy.2011.02.023}, author = {Chavan, Subhash P. and Harale, Kishor R. and Dumare, Nilesh B. and Kalkote, Uttam R.} }