@article { ISI:000293168000044,
	title = {Novel hybrids of fluconazole and furanones: design, synthesis and antifungal activity},
	journal = {Bioorganic \& Medicinal Chemistry Letters},
	volume = {21},
	number = {16},
	year = {2011},
	month = {AUG},
	pages = {4873-4878},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>During our efforts to develop new antifungal agents, a number of hybrid molecules containing furanones and fluconazole pharmacophores were designed and synthesized. The new chemical entities thus synthesized were tested for their potential as antifungal agents against various fungal strains and it was observed that the compounds with general structure 7 were potent inhibitors of Candida albicans ATCC 24433, Candida glabrata ATCC 90030, Candida tropicalis ATCC 750 and Candida neoformans ATCC 34664 while the fluconazole analogues 12 exhibited antifungal activity against Candida albicans ATCC 24433 and Candida glabrata ATCC 90030. The structure-activity relationship for these compounds is discussed. The synthetic strategies used in the present work have potential to prepare a large number of compounds for further refinement of structures to obtain molecules suitable for development as antifungal drugs. (C) 2011 Elsevier Ltd. All rights reserved.</p>},
	keywords = {Antifungal activity, Fluconazole, Furanones},
	issn = {0960-894X},
	doi = {10.1016/j.bmcl.2011.06.022},
	author = {Borate, Hanumant B. and Sawargave, Sangmeshwer P. and Chavan, Subhash P. and Chandavarkar, Mohan A. and Iyer, Ramki and Tawte, Amit and Rao, Deepali and Deore, Jaydeep V. and Kudale, Ananada S. and Mahajan, Pankaj S. and Kangire, Gopinath S.}
}
@article { ISI:000341083400001,
	title = {Novel, concise and efficient protocol for non-natural piperidine compounds},
	journal = {RSC Advances},
	volume = {4},
	number = {62},
	year = {2014},
	month = {JUL},
	pages = {32594-32598},
	publisher = {ROYAL SOC CHEMISTRY},
	address = {THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND},
	abstract = {<p>Formal synthesis of L-altro-1-deoxynojirimycin, cis-3-hydroxypipecolic acid along with synthesis of (R)-piperidinol and a conceptually different advanced intermediate for non-natural piperidine alkaloids is reported from cis-butene-1,4-diol. The key reactions involved are Johnson-Claisen rearrangement, Sharpless asymmetric dihydroxylation, reductive lactamization and novel regioselective elimination.</p>},
	issn = {2046-2069},
	doi = {10.1039/c4ra04558k},
	author = {Chavan, Subhash P. and Dumare, Nilesh B. and Pawar, Kailash P.}
}
