@article { ISI:000308778100017,
	title = {Highly diastereoselective total synthesis of (+/-)-heritonin and (+/-)-heritol},
	journal = {Tetrahedron},
	volume = {68},
	number = {40},
	year = {2012},
	month = {OCT},
	pages = {8509-8514},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>A highly diastereoselective synthesis of heritol and heritonin by intramolecular cyclization on a preformed sensitive butenolide functionality is described. (C) 2012 Elsevier Ltd. All rights reserved.</p>},
	keywords = {Butenolide, cyclization, Dihydroxylation, Friedel-Crafts acylation, Tetralone},
	issn = {0040-4020},
	doi = {10.1016/j.tet.2012.07.020},
	author = {Chavan, Subhash P. and Garai, Sumanta and Kalkote, Uttam R.}
}
@article {46634,
	title = {Scalable synthesis of 3-Ethyl-4-methyl-1,5-dihydro-2H-pyrrol-2-one: an important building block of the antidiabetic drug glimepiride},
	journal = {Synthesis-Stuttgart},
	volume = {52},
	year = {2020},
	month = {NOV},
	pages = {3480-3484},
	type = {Article},
	abstract = {<p>A four-step, practical, and easily scalable synthesis of 3-ethyl-4-methyl-1,5-dihydro-2H-pyrrol-2-one, an important building block of the antidiabetic drug glimepiride, has been accomplished. Key features are the synthesis of 3-methyl-4-hydroxy-2-butenolide in water and triflic acid mediated N-benzyl lactam N-deprotection. The main advantages of this process are the scalable synthetic route and decreased number of reaction steps, which paves the way for the industrial-scale synthesis of 3-ethyl-4-methyl-1,5-dihydro-2H-pyrrol-2-one.</p>
},
	keywords = {antidiabetic drug, Butenolide, glimepiride, lactams, scalable synthesis},
	issn = {0039-7881},
	doi = {10.1055/s-0040-1707344},
	author = {Chavan, Subhash P. and Pawar, Ambaji A. and Patil, Niteen B. and Kadam, Appasaheb L. and Shinde, Shrikrishna S.}
}
