@article {48143,
	title = {Ready access to densely substituted furans using Tsuji-Wacker type cyclization},
	journal = {Journal of Organic Chemistry},
	volume = {87},
	year = {2022},
	month = {JAN },
	pages = {556-568},
	type = {Article},
	abstract = {<p>
	A competent method for the construction of highly substituted furans catalyzed by Pd(II) and Cu(II) chloride has been developed. The method provides easy access to di-, tri-, and tetrasubstituted furans from corresponding diols with relatively mild conditions in a unified strategy. The developed method has been successfully tested with more than 25 substrates, which resulted in furans of multiple substitution patterns with up to 84\% isolated yields.</p>
},
	issn = {0022-3263},
	doi = {10.1021/acs.joc.1c02567},
	author = {Masal, Dattatraya P. and Choudhury, Rahul and Singh, Aman and Reddy, D. Srinivasa}
}
@article {49923,
	title = {Ready access to benzodiazocines from tryptamines: a druggable scaffold toward antiviral agents},
	journal = {ACS Medicinal Chemistry Letters},
	volume = {16},
	year = {2025},
	month = {DEC},
	pages = {2362-2367},
	type = {Article},
	abstract = {<p>
	Herein we report the first synthesis of the proposed structure of a benzodiazocine natural product, peganutonin A. Considering the druggable nature of benzodiazocine and its limited exploration in the field of medicinal chemistry, we generalized the approach and created a library of compounds useful for various biological activities. Key steps in present approach include tryptamine cyclization facilitated by tert-butyl hypochlorite and cleavage of the fused indole ring using ozonolysis. Preliminary screening of the synthesized compounds resulted in potent antiviral compounds against the SARS-CoV-2 virus.</p>
},
	keywords = {Benzodiazocine, drug discovery, Indole cleavage, Lipinski{\textquoteright}s rule of Five, SARS-CoV-2 inhibition, Tryptamine},
	issn = {1948-5875},
	doi = {10.1021/acsmedchemlett.5c00527},
	author = {Saranya, N. Sathya Sai and Choudhury, Rahul and Routholla, Ganesh and Supekar, Prathmesh R. and R, Nandhakumaar and Martin, Alna Kuriyickal and Muruganandham, Renuga Devi and Kumar, Bokara Kiran and Reddy, D. Srinivasa}
}
