@article {48042,
	title = {Metal- and light-free direct C-3 ketoalkylation of quinoxalin-2(1H)-ones with cyclopropanols in aqueous medium},
	journal = {ChemistrySelect},
	volume = {7},
	year = {2022},
	month = {OCT},
	pages = {e202203597},
	type = {Article},
	abstract = {<p>
	Direct oxidative C-3 ketoalkylation of quinoxalin-2(1H)-ones with cyclopropanols using ammonium persulfate in an aqueous medium has been achieved in a moderate to good yield. The reaction does not require metals, light-source, or catalysts to facilitate the reaction and could be efficiently utilized to construct a wide range of biologically relevant 3-ketoalkylated quinoxalin-2(1H)-ones.</p>
},
	keywords = {aqueous medium, cyclopropanols, ketoalkylation, metal-free, quinoxalin-2(1H)-ones},
	issn = {2365-6549},
	doi = {10.1002/slct.202203597},
	author = {More, Devidas A. and Mujahid, M. and Muthukrishnan, M.}
}
@article {49226,
	title = {Visible-light mediated C-3 amination of quinoxalin-2(1H)-ones via electron donor-acceptor complexation},
	journal = {Asian Journal of Organic Chemistry},
	volume = {13},
	year = {2024},
	month = {AUG},
	type = {Article},
	abstract = {<p>
	The formation of carbon-nitrogen bonds holds paramount importance in the realm of synthetic organic chemistry, finding extensive applications in the synthesis of pharmaceuticals, agrochemicals, and organic materials. Herein, we describe a novel EDA complex mediated, metal- and photocatalyst-free, visible-light-initiated direct C-3 amination of biologically important, quinoxalin-2(1H)-one moiety. The key to the success lies in the formation of a photoactivated electron donor-acceptor complex between quinoxalin-2(1H)-one and amine, which undergo subsequent electron transfer reaction to effect the desired transformation. A diverse array of 3-aminoquinoxalin-2(1H)-ones were prepared employing this process and the yields are up to 87\%. This work represents a significant advancement toward a more environmentally friendly and efficient approach, characterized by mild reaction conditions and a high atom economy.</p>
},
	keywords = {C-3 amination, Dehydrogenative amination, EDA complex, quinoxalin-2(1H)-ones},
	issn = {2193-5807},
	doi = {10.1002/ajoc.202400150},
	author = {More, Devidas A. and Gayathri, P. R. and Thete, Kishor R. and Muthukrishnan, M.}
}
