@article {46137,
	title = {Neural anti-inflammatory natural product periconianone A: total synthesis and biological evaluation},
	journal = {European Journal of Organic Chemistry},
	year = {2019},
	month = {APR },
	pages = {2376-2381},
	type = {Article},
	abstract = {<p>Total synthesis of periconianone A, an eremophilane-type sesquiterpenoid with impressive neural anti-inflammatory potential, has been accomplished. Diels-Alder/aldol strategy to construct tetrahydro-naphthalene-2,6-dione scaffold, allylic oxidation of dienone using DBU/O-2 and postulated biomimetic aldol reaction to construct 6/6/6 tricyclic system are the highlights of the present synthesis. Furthermore, the synthesized (+/-)-periconianone A and two close analogs were tested for their neural anti-inflammatory activity using various assays. In the course of our study we found a structurally simplified analog is superior to (+/-)-periconianone A.</p>
},
	keywords = {Aldol, Allylic oxidation, Biological evaluation, Cytotoxicity, Diels-Alder, Periconianone A},
	issn = {1434-193X},
	doi = {10.1002/ejoc.201900048},
	author = {Kalmode, Hanuman P. and Patil, Suhag S. and Handore, Kishor L. and Athawale, Paresh R. and Dandela, Rambabu and Verma, Abhishek Kumar and Basu, Anirban and Reddy, D. Srinivasa}
}
@article {48097,
	title = {Total synthesis of 12, 13-dibenzyl-banistenoside B and analogs},
	journal = {European Journal of Organic Chemistry},
	volume = {2022},
	year = {2022},
	month = {MAY},
	pages = {e202200222},
	type = {Article},
	abstract = {<p>
	Banistenosides A and B possessing a unique {\textquoteleft}{\textquoteleft}azepino(1,2-a)tetrahydro-beta-carboline{\textquoteright}{\textquoteright} carbon framework were isolated from the stem of Banisteriopsis caapi and showed MAO-A inhibition. Herein, we report the total synthesis of dibenzyl derivative of the untouched natural product in the last two decades, Banistenoside B. The key steps involve construction of 6.5.6.7 tetracyclic core using Pictet-Spengler reaction and intramolecular amide coupling. The stereoselective glycation was achieved through Hotha{\textquoteright}s protocol using gold catalyst, and silver triflate in the late stage of synthesis. The stereochemistry of most of the essential compounds were confirmed by X-ray crystallography.</p>
},
	keywords = {Au-catalyst, Multiple steps total synthesis, Natural products, Pictet-Spengler reaction, Wittig reaction},
	issn = {1434-193X},
	doi = {10.1002/ejoc.202200222},
	author = {Patil, Suhag S. and Jachak, Gorakhnath R. and Krishna, Gamidi Rama and Argade, Narshinha P. and Reddy, D. Srinivasa}
}
