@article {47642,
	title = {Studies directed toward the synthesis of hedycoropyrans: total synthesis of des-hydroxy (-)-hedycoropyran B (ent-rhoiptelol B)},
	journal = {Organic \& Biomolecular Chemistry},
	volume = {20},
	year = {2022},
	month = {JAN },
	pages = {444-463},
	type = {Article},
	abstract = {A full account of our efforts directed towards the synthesis of the diarylheptanoid-derived natural products hedycoropyrans that led to the total synthesis of ent-rhoiptelol B is described. In this endeavor, we have attempted two distinct synthetic strategies to access hedycoropyrans A and B, which led us to establish a facile synthetic route for des-hydroxy (-)-hedycoropyran B (ent-rhoiptelol B) from simple and readily accessible building blocks of 4-allylanisole and vanillin, employing Sharpless asymmetric epoxidation, CBS reduction, and an intramolecular AgOTf-catalyzed oxa-Michael reaction of suitably functionalized hydroxy-ynone as key transformations. The investigations disclosed herein will provide insights into designing novel synthetic routes for THP-DAH-derived natural products.},
	issn = {1477-0520},
	doi = {10.1039/d1ob01972d},
	author = {Kataria, Priyanka and Nomula, Rajesh and Kontham, Ravindar}
}
@article {48045,
	title = {Studies directed toward the total synthesis of nannocystin A},
	journal = {ChemistrySelect},
	volume = {7},
	year = {2022},
	month = {NOV},
	pages = {e202203893},
	type = {Article},
	abstract = {<p>
	A full account of our efforts directed toward the stereoselective total synthesis of nannocystin A, a macrocyclic myxobacterial metabolite, is presented. In this endeavor, we have attempted two distinct synthetic routes to access polyketide fragment (C1-C11) of macrocyclic depsipeptide (21-membered) natural product from readily accessible building blocks 1,3-propanediol and benzaldehyde employing Evans aldol, CBS reduction, Heck cross-coupling, and Sharpless asymmetric epoxidation as key transformations. Ultimately, accomplished the synthesis of the complete skeleton (21-membered precursor for macrocyclic depsipeptide) of the nannocystin A possessing desired stereochemistry and functional groups.</p>
},
	keywords = {amidation, Depsipeptide, Evans aldol reaction, Macrocycle, Nannocystins},
	issn = {2365-6549},
	doi = {10.1002/slct.202203893},
	author = {Nomula, Rajesh and Pratapure, Madhukar S. and Kontham, Ravindar}
}
