@article {46796,
	title = {Anthrone-spirolactam and quinoline hybrid based sensor for selective fluorescent detection of Fe(3+)ions},
	volume = {34},
	year = {2020},
	month = {OCT},
	pages = {e5867},
	type = {Article},
	abstract = {<p>The synthesis of a novel, and highly selective Fe(3+)ion sensor based on anthrone-spirolactam and its quinoline hybrid ligand is reported. The designed ligand displayed selective detection of Fe(3+)ions with enhanced fluorescence emission. The complexation of Fe(3+)ion led to a red shift of 32 nm from 420 nm to 452 nm, and a several fold increase in intensity with fluorescent green emission. The complexation (detection) of Fe(3+)ions with ligand resulted in chelation enhanced fluorescence and intramolecular charge transfer through the inhibition of C=N isomerization. This hybrid sensor shows high sensitivity and selectivity, spontaneous response, and works on a wide pH range a minimum detection limit of 6.83 x 10(-8)M. Importantly, the sensor works through the fluorescence turn-on mechanism that overcomes the paramagnetic effect of Fe(3+)ions. The binding mechanism between the ligand and the Fe(3+)ions was established from the Job{\textquoteright}s plot method, optical studies, Fourier transfor infrared spectroscopy, NMR titration, fluorescence life-time studies, and density functional theory optimization. The sensor displayed excellent results in the quantification of Fe(3+)ions from real water samples. Furthermore, due to its biocompatibility nature, fluorescent spotting of Fe(3+)ions in live cells revealed its bioimaging applications.</p>
},
	keywords = {anthrone-spirolactam-quinoline, Cell imaging, fluorescence, intramolecular charge transfer, iron},
	issn = {0268-2605},
	doi = {10.1002/aoc.5867, Early Access Date = JUL 2020},
	author = {Darole, Ratanamala S. and Christopher Leslee, Denzil Britto and Mukherjee, Anagh and Gonnade, Rajesh G. and Karuppannan, Sekar and Senthilkumar, Beeran}
}
@article {49502,
	title = {Accessing polysubstituted 2-cyclopentenones via base-mediated annulation of β-keto esters and phenacyl bromides},
	journal = {Organic \& Biomolecular Chemistry},
	volume = {23},
	year = {2025},
	month = {MAY},
	pages = {4519-4524},
	type = {Article},
	abstract = {<p>
	A transition metal-free method is demonstrated for the synthesis of polysubstituted 2-cyclopentenone compounds, which involves the direct annulation of phenacyl bromide with beta-keto esters in a single step. This process proceeds through a base-mediated SN2 nucleophilic substitution, followed by an intramolecular aldol condensation, resulting in the formation of three C-C bonds and one ring in a cascade manner. The experimental results achieved a record high yield of highly substituted diverse 2-cyclopentenone analogues, which exhibit very good structural resemblance to biologically significant natural compounds.</p>
},
	issn = {1477-0520},
	doi = {10.1039/d4ob02088j},
	author = {Kumar, Mohit and Paul, Vincent and Gamidi, Rama Krishna and Senthilkumar, Beeran}
}
