@article {47997,
	title = {Metal-free aminocarbonylation of p-quinone methides with isocyanides: synthesis of sterically hindered alpha-arylated acetamides},
	journal = {Chemistry-an Asian Journal},
	volume = {17},
	year = {2022},
	month = {OCT},
	pages = {e202200642},
	type = {Article},
	abstract = {<p>
	The synthesis of sterically hindered alpha-arylated acetamides generally requires a multistep reaction sequence and is also difficult to access due to steric constraints. This protocol allows the synthesis of sterically hindered alpha-arylated acetamides in moderate to high yields via 1,6-addition of isocyanides to p-quinone methides in the presence of BF3 center dot OEt2. The present transformation features transition metal-free conditions, avoiding the use of toxic carbon monoxide, broad substrate scope, mild reaction conditions, and operational simplicity.</p>
},
	keywords = {Aminocarbonylation, Isocyanide, p-Quinone methide, Sterically Hindered alpha-Arylated Acetamides},
	issn = {1861-4728},
	doi = {10.1002/asia.202200642},
	author = {Shirsath, Sachin R. and More, Devidas A. and Muthukrishnan, M.}
}
@article {48698,
	title = {Metal- and photocatalyst-free, visible-light-initiated C3 a-aminomethylation of quinoxalin-2(1H)-ones via electron donor-acceptor complexes},
	journal = {Journal of Organic Chemistry},
	volume = {88},
	year = {2023},
	month = {AUG },
	pages = {13339-13350},
	type = {Article},
	abstract = {<p>
	We report a metal- and photocatalyst-free C3 a-aminomethylation of quinoxalin-2(1H)-ones with N-alkyl-N-methylanilines. The reaction proceeds through the formation of a photoactivated electron donor-acceptor complex between quinoxalin-2(1H)-ones and N-alkyl-N-methylanilines. The present method provides a mild and environmentally friendly protocol that exhibits good atom economy and excellent functional group tolerance to obtain a library of biologically significant C3 a-aminomethylated quinoxalin-2(1H)-ones in good yields.</p>
},
	issn = {0022-3263},
	doi = {10.1021/acs.joc.3c01249},
	author = {More, Devidas A. and Shirsath, Sachin R. and Muthukrishnan, M.}
}
