@article {45376,
	title = {Removable functional group strategy for regiodivergent Wittig rearrangement products},
	journal = {Organic \& Biomolecular Chemistry },
	volume = {16},
	year = {2018},
	month = {DEC},
	pages = {8922-8926},
	type = {Article},
	abstract = {1,2] and [2,3] Wittig rearrangements are competing reaction pathways, often leading to uncontrollable product distribution. We employ a single removable functional group to fulfill the dual role of attaining a reversible [2,3] and stabilizing radical intermediate for the [1,2] path to obtain both the Wittig products selectively for a broad range of substrates.},
	issn = {1477-0520},
	doi = {10.1039/c8ob02221f},
	author = {Alam, Md Nirshad and Lakshmi, K. M. and Maity, Pradip}
}
@article {47079,
	title = {[1,3]-Claisen rearrangement via removable functional group mediated radical stabilization},
	journal = {Organic Letters},
	volume = {23},
	year = {2021},
	month = {FEB },
	pages = {890-895},
	type = {Article},
	abstract = {<p>A thermal O-to-C [1,3]-rearrangement of alpha-hydroxy acid derived enol ethers was achieved under mild conditions. The 2-aminothiophenol protection of carboxylic acids facilitates formation of the [1,3] precursor and its thermal rearrangement via stabilization of a radical intermediate. Experimental and theoretical evidence for dissociative radical pair formation, its captodative stability via aminothiophenol, and a unique solvent effect are presented. The aminothiophenol was deprotected from rearrangement products as well as after derivatization to useful synthons.</p>
},
	issn = {1523-7060},
	doi = {10.1021/acs.orglett.0c04109},
	author = {Alam, Md Nirshad and Dash, Soumya Ranjan and Mukherjee, Anirban and Pandole, Satish and Marelli, Udaya Kiran and Vanka, Kumar and Maity, Pradip}
}
@article {47594,
	title = {Phosphite mediated asymmetric N to C migration for the synthesis of chiral heterocycles from primary amines},
	journal = {Chemical Science},
	volume = {12},
	year = {2021},
	month = {JUL},
	pages = {8996-9003},
	type = {Article},
	abstract = {A phosphite mediated stereoretentive C-H alkylation of N-alkylpyridinium salts derived from chiral primary amines was achieved. The reaction proceeds through the activation of the N-alkylpyridinium salt substrate with a nucleophilic phosphite catalyst, followed by a base mediated [1,2] aza-Wittig rearrangement and subsequent catalyst dissociation for an overall N to C-2 alkyl migration. The scope and degree of stereoretention were studied, and both experimental and theoretical investigations were performed to support an unprecedented aza-Wittig rearrangement-rearomatization sequence. A catalytic enantioselective version starting with racemic starting material and chiral phosphite catalyst was also established following our understanding of the stereoretentive process. This method provides efficient access to tertiary and quaternary stereogenic centers in pyridine systems, which are prevalent in drugs, bioactive natural products, chiral ligands, and catalysts.},
	issn = {2041-6520},
	doi = {10.1039/d1sc01217g},
	author = {Rani, Soniya and Dash, Soumya Ranjan and Bera, Asish and Alam, Md Nirshad and Vanka, Kumar and Maity, Pradip}
}
@article {48346,
	title = {Blue fluorescence of cyano-tryptophan predicts local electrostatics and hydrogen bonding in biomolecules},
	journal = {Journal of Physical Chemistry B},
	volume = {126},
	year = {2022},
	month = {DEC},
	pages = {10732-10740},
	type = {Article},
	abstract = {<p>
	Cyano-tryptophan is an unnatural fluorescent amino acid that emits in the visible region. Along with the structural similarity with tryptophan, the unique photophysical properties of this fluorophore make it an ideal probe for biophysical research. Herein, combining fluorescence spectroscopy, infrared spectroscopy, and molecular dynamics simulations, we show that the cyano-tryptophan{\textquoteright}s emission energy quantifies the underlying bond-specific noncovalent interactions in terms of the electric field. We further report the use of fluorophore{\textquoteright}s emission energy to predict its hydrogen bond characteristics. We demonstrate that combining experiments with molecular dynamics simulations can provide the hydrogen bonding status of the nitrile moiety. In addition, we report a method to differentiate between aqueous and nonaqueous hydrogen-bonding partners. Using a phenomenological approach, we demonstrate that the presence of the cyano-indole moiety is responsible for the distinct correlations between the fluorophore{\textquoteright}s emission and the electrostatic forces on the nitrile bond. As indole is a privileged scaffold for both native amino acids and nucleobases, cyano-indoles will have many multifaceted applications.</p>
},
	issn = {1520-6106},
	doi = {10.1021/acs.jpcb.2c05848},
	author = {Haldar, Tapas and Chatterjee, Srijan and Alam, Md Nirshad and Maity, Pradip and Bagchi, Sayan}
}
