@article {43879,
	title = {Pd-catalyzed regioselective mono-arylation: quinazolinone as the inherent directing group for C(sp(2))-H activation},
	journal = {Journal of Organic Chemistry},
	volume = {82},
	year = {2017},
	month = {JUN},
	pages = {6366-6372},
	type = {Article},
	chapter = {6366-6372},
	abstract = {<p>The Pd-catalyzed quinazolinone-directed regioselective monoarylation of aromatic rings by C-H bond activation is developed. A broad substrate scope is demonstrated for both quinazolinone as well as diary-liodonium triflates. The use of a base was found to be crucial for this transformation, unlike for the known nitrogen-directed arylations. All of the novel quinazolinones of biological interest were synthesized by using the operationally simple Pd(II)-catalyzed arylation reaction.</p>},
	keywords = {Aromatic rings, catalysis, Chemical activation, Chemical reactions, Palladium compounds, Regioselectivity},
	issn = {0022-3263},
	doi = {10.1021/acs.joc.7b00948},
	author = {Garad, Dnyaneshwar N. and Viveki, Amol B. and Mhaske, Santosh B.}
}
@article {46995,
	title = {Highly enantioselective synthesis of sitagliptin},
	journal = {Asian Journal of Organic Chemistry},
	volume = {9},
	year = {2020},
	month = {FEB},
	pages = {189-191},
	type = {Article},
	abstract = {<p>A highly enantioselective synthesis of sitagliptin, a potent DPP-4 inhibitor, is reported. Explicitly identified chiral FerroLANE ligands in the presence of rhodium catalyze the asymmetric hydrogenation of an enamine to yield sitagliptin with excellent enantioselectivity (98\% ee). The process was scaled up to 5 g and the final product was isolated as a phosphate salt with \&gt;99\% ee.</p>
},
	keywords = {asymmetric hydrogenation, catalysis, FerroLANE ligands, Rhodium, sitagliptin},
	issn = {2193-5807},
	doi = {10.1002/ajoc.201900709, Early Access Date = JAN 2020},
	author = {Khopade, V. Kishor and Sen, Anirban and Birajdar, Rajkumar S. and Paulbudhe, Uday P. and Kavale, Dattatry S. and Shinde, Prashant S. and Mhaske, Santosh B. and Chikkali, Samir H.}
}
