@article {44468, title = {Transition metal free regio-selective C{\textendash}H hydroxylation of chromanones towards the synthesis of hydroxyl-chromanones using PhI(OAc)2 as the oxidant}, journal = {Chemical Communications}, volume = {54}, year = {2018}, month = {FEB}, pages = {2252-2255}, type = {Journal Article}, abstract = {

The chromanone scaffold is considered as a privileged structure in drug discovery. Herein, we report a highly efficient PhI(OAc)2 mediated regioselective, direct C{\textendash}H hydroxylation of chromanones. This method offers easy access to substituted 6-hydroxy chromanones in moderate to good isolated yields, thus paving the way for their pharmaceutical studies.

}, issn = {13597345}, doi = {10.1039/C7CC08588E}, author = {Viswanadh, N.}, editor = {Ghotekar, Ganesh S.} } @article {45599, title = {Total synthesis of marine natural products serinolamide A and columbamide D}, journal = {ACS Omega}, volume = {4}, year = {2019}, month = {JAN}, pages = {1322{\textendash}1328}, type = {Article}, abstract = {

In this report, an expeditious synthesis of two new biologically active marine natural products serinolamide A and columbamide D is documented. This convergent approach involves the key steps such as hydrolytic kinetic resolution, cross metathesis, Grignard reaction, Johnson{\textendash}Claisen rearrangement, Mitsunobu, and so forth. Both of the target molecules were obtained from a common precursor (R)-7 with high enantioselectivity, less synthetic steps, and in good overall yields (serinolamide A 66\% and columbamide D 62\%).

}, doi = {10.1021/acsomega.8b03417}, author = {Ghotekar, G. S. and Mujahid, M. and Muthukrishnan, M.} } @article {46195, title = {Transition-metal-free benzannulation of tricarbonyl derivatives with arynes: access to 1,3-dinaphthol precursors for the synthesis of rhodamine dye analogues}, journal = {Journal of Organic Chemistry}, volume = {84}, year = {2019}, month = {FEB}, pages = {2269-2276}, type = {Article}, abstract = {

Herein, we report a transition-metal-free annulation reaction of benzynes and 1,3-oxopentanedioate for the synthesis of highly functionalized naphthalene derivatives for the first time. Additionally, the representative naphthalene derivatives have been successfully transformed into the new series of rhodamine dye analogues.

}, issn = {0022-3263}, doi = {10.1021/acs.joc.8b02560}, author = {Ghotekar, Ganesh S. and Shaikh, Aslam C. and Muthukrishnan, M.} } @article {48113, title = {Thallium(III) p-tosylate (TTS) mediated oxidative rearrangement of 2-naphthyl and 2-heteroarylchromanones}, journal = {Indian Journal of Chemistry}, volume = {61}, year = {2022}, month = {SEP}, pages = {923-927}, type = {Article}, abstract = {

A practical and effective approach towards the synthesis of 3-hetroaryl-4H-chromen-4-ones by the oxidative rearrangement of the respective 2-hetroaryl chroman-4-ones using thallium(III) p-tosylate is described. The oxidative rearrangement of alpha and beta-naphthyl and thiophene behave like aryl groups. However, pyridyl groups give only the dehydrogenated product.

}, keywords = {2-(3-pyridyl)chromones, 2-(4-pyridyl)chromones, 2-and 3-(2-theinyl)chromones, 2-and 3-(3-theinyl)chromones, 2-and 3-(?-naphthyl) chromones, Dehydrogenation, Oxidative rearrangements, thallium(III) acetate, thallium(III) p-tosylate}, issn = {0019-5103}, doi = {10.56042/ijc.v61i9.66341}, author = {Kurapati, Chidvilas and Muthukrishnan, M. and Singh, V. Om and Gundla, Rambabu} }