@article { ISI:000356370500002,
	title = {Preferential enrichment of DL-leucine using cocrystal formation with oxalic acid under nonequilibrium crystallization conditions},
	journal = {Chirality},
	volume = {27},
	number = {7},
	year = {2015},
	month = {JUL},
	pages = {405-410},
	publisher = {WILEY-BLACKWELL},
	address = {111 RIVER ST, HOBOKEN 07030-5774, NJ USA},
	abstract = {<p>By utilizing the preferential enrichment (PE) technique, we achieved an improved enantiomeric resolution of DL-leucine (Leu) using a 1:1 cocrystal (DL-1) of DL-Leu and oxalic acid. The crystal structure analysis of DL-1 indicated the occurrence of a novel type of phase transition and subsequent preferential redissolution of one enantiomer from the resulting crystals into solution. Chirality 27:405-410 2015. (c) 2015 Wiley Periodicals, Inc.</p>},
	keywords = {chiral resolution, cocrystal formation, leucine, phase transition, preferential enrichment},
	issn = {0899-0042},
	doi = {10.1002/chir.22431},
	author = {Manoj, Kochunnoonny and Takahashi, Hiroki and Morita, Yoko and Gonnade, Rajesh G. and Iwama, Sekai and Tsue, Hirohito and Tamura, Rui}
}
@article {48124,
	title = {Polymorphs of green fluorescence protein chromophore analogue: fluorescence switching with thermal stimuli},
	journal = {Crystal Growth \& Design},
	volume = {22},
	year = {2022},
	month = {MAR },
	pages = {1892-1905},
	type = {Article},
	abstract = {<p>
	Polymorphs of fluorescent organic materials offer significant implications in optoelectronics and advanced materials as they modulate photoluminescence properties. A slight alteration in the conformation/packing of molecules in the crystals shows variation in photoluminescence. This necessitates the polymorph screening of these materials to develop novel crystalline forms with distinct fluorescence emissions for broader application. In continuation of our work on the polymorph screening of Green Fluorescence Protein Chromophore (GFPc), we have synthesized a new imidazoline derivative, ethyl (Z)-2-(2-methyl-5-oxo-4-(3,4,5-trimethoxybenzylidene)-4,5-dihydro-1H-imi dazol-1- yl)acetate (1). Polymorph screening of 1 under different crystallization conditions revealed three polymorphs, Form I (needle), Form II (block), and Form III (polycrystalline material). Forms I and II are the outcome of solution crystallization, whereas Form III was produced from the melt crystallization of Forms I and II. DSC, HSM, and powder and single-crystal XRD studies indicate the conversion of Form I and Form III crystals to Form II crystals on thermal stimuli. The photoluminescence studies revealed cyan, yellow, and yellowish-green fluorescence emission for Forms I, II, and III crystals, respectively. The difference in photoluminescence could be due to the variance in aggregation modes like H-aggregation in Form I and J-aggregation in Form II crystals. Form I, Form II, and Form III crystals also showed irreversible thermal fluorescent switching from cyan-yellow-green due to polymorphic phase transitions. The study correlates the direct observation of the modulation of the excited-state transition under thermal stimuli in the crystalline phase. It will help augment the pace in the research of thermally responsive fluorescent materials.</p>
},
	issn = {1528-7483},
	doi = {10.1021/acs.cgd.1c01459},
	author = {Mali, Bhupendra P. and Dash, Soumya Ranjan and Biswas, Anupam and Vanka, Kumar and Manoj, Kochunnoonny and Gonnade, Rajesh G.}
}
