@article {44151,
	title = {Total synthesis of (+/-)/(+)-subincanadine E and determination of absolute configuration},
	journal = {Journal of Organic Chemistry},
	volume = {82},
	year = {2017},
	month = {OCT},
	pages = {11126-11133},
	type = {Article},
	abstract = {A facile synthesis of (+/-)-subincanadine E was described from tryptamine-based maleimide. 1,2-Addition of Grignard reagent to maleimide, internal activation of formed lactamol for in situ 1,4-addition of Grignard reagent, and associated position-specific allylic rearrangement in diastereoselective Pictet-Spengler cyclization were the key steps. Enantioselective first total synthesis of naturally occurring cytotoxic (+)-subincanadine E was also accomplished from (S)-acetoxysuccinimide via an unusual syn-addition of cuprate to the alpha/beta-unsaturated lactam. Sinister absolute configuration was assigned to (+)-subincanadine E on the basis of total synthesis. (S)-Acetoxy group in the succinimide precursor was initially employed to impart regio- and stereoselectivity and then as a suitable leaving group to generate the desired conjugated lactam.},
	doi = {10.1021/acs.job.7b02122},
	author = {Kalshetti, Manojkumar G. and N. P. Argade}
}
@article {45426,
	title = { Regioselective and stereoselective reductive aziridinium ring cleavage leading to azabicyclodecane architecture: enantioselective synthesis of (+)-subincanadine F},
	journal = {Journal of Organic Chemistry},
	volume = {83},
	year = {2018},
	month = {OCT},
	pages = {12164-12170},
	type = {Article},
	abstract = {Enantioselective synthesis of cytotoxic indole alkaloid (+)-subincanadine F was accomplished starting from the corresponding (S)-acetoxysuccinimide via aziridinium ring formation and its reductive ring expansion route. Regioselective and stereoselective reductive aziridinium carbon-nitrogen bond cleavage comprising ring expansions was a key step. The (S)-OMOM protection of the hydroxyl moiety adjacent to a benzylic carbon of an in situ formed aziridinium system was necessary for lithium borohydride-induced reductive ring expansions, and it also served as a latent source of an essential ketone carbonyl group for the generation of an alpha,beta-conjugated system.},
	issn = { 0022-3263},
	doi = {10.1021/acs.joc.8b02113},
	author = {Kalshetti, Manojkumar G. and Argade, Narshinha P.}
}
@article {45554,
	title = {Progress in total synthesis of subincanadine alkaloids and their congeners},
	journal = {Organic \& Biomolecular Chemistry},
	volume = {17},
	year = {2019},
	month = {JAN},
	pages = {745-761},
	type = {Article},
	abstract = {<p>A concise account of isolation, characterization, bioactivity, plausible biogenetic pathways, and most importantly, total synthesis of structurally fascinating and biologically imperious indole-based subincanadine alkaloids and their biogenetic congeners are described in the present review with special emphasis on total synthesis and therein an involved set of key reactions.</p>},
	issn = {1477-0520},
	doi = {10.1039/c8ob02565g},
	author = {Kalshetti, Manojkumar G. and Argade, Narshinha P.}
}
@article {47497,
	title = {Stereoselective synthesis of subincanadine alkaloids framework},
	journal = {Indian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry},
	volume = {58},
	year = {2019},
	month = {JUN},
	pages = {669-673},
	type = {Article},
	abstract = {Starting from, N-tosyltryptamine and (S)-acetoxysuccinic anhydride, a facile synthesis of (-)-indolizinoindolone has been demonstrated as a basic structural outline of bioactive subincanadine alkaloids. Regioselective Grignard reaction with (S)-acetoxysuccinimide, stereoselective intramolecular cyclization to form (-)-indolizinoindolone skeleton and TiCl4 induced condensation with acetaldehyde for stereoselective generation of exocyclic carbon carbon double bond are the key features.},
	keywords = {(S)-Acetoxysuccinimide, alane reduction, condensation, Grignard reaction, indolizinoindolone, PCC-oxidation, stereoselective Pictet-Spengler cyclization},
	issn = {0376-4699},
	author = {Kalshetti, Manojkumar G. and Argade, Narshinha P.}
}
