@article {43869, title = {Metal-free radical trifluoromethylation of beta-nitroalkenes through visible-light photoredox catalysis}, journal = {Chemical Communications}, volume = {53}, year = {2017}, month = {JUN}, pages = {6760-6763}, type = {Article}, abstract = {A catalytic method for functional group interconversion is immensely important in modern sciences. Here, we report an efficient catalytic conversion of nitroalkenes to highly stereoselective 1-trifluoromethylalkenes at room temperature. This unprecedented metal-free photocatalytic strategy is simple and operates under visible-light irradiation using the commercially available CF3 source.}, doi = {10.1039/c7cc02589k}, author = {Midya, Siba P. and Rana, Jagannath and Abraham, Thomas and Aswin, Bhaskaran and Balaraman, Ekambaram} } @article {43732, title = {Predesigned metal-anchored building block for in situ generation of Pd nanoparticles in porous covalent organic framework: application in heterogeneous tandem catalysis}, journal = {ACS Applied Materials \& Interfaces}, volume = {9}, year = {2017}, month = {APR}, pages = {13785-13792}, type = {Article}, abstract = {The development of nanoparticle-polymer-hybrid-based heterogeneous catalysts with high reactivity and good recyclability is highly desired for their applications in the chemical and pharmaceutical industries: Herein, we have developed a novel synthetic strategy by choosing a predesigned metal-anchored building block for in situ generation of metal (Pd) nanoparticles in the stable, porous, and crystalline covalent organic framework (COF), without using conventional reducing agents. In situ generation of Pd nanoparticles in the COF Skeleton is explicitly confirmed{\textquoteright} from PXRD, XPS, TEM images, and N-15 NMR spectral analysis. This hybrid material is found to be an excellent reusable heterogeneous catalyst for the synthesis of biologically and pharmaceutically important 2-substituted benzofurans from 2-bromophencils and terminal alkynes via a tandem process with the turnover number up to 1101. The heterogeneity of the catalytic process is unambiguously verified by a mercury poisoning experiment and leaching test. This hybrid material shows superior catalytic performance compared to commercially available homogeneous as well as heterogeneous Pd catalysts.}, doi = {10.1021/acsami.7b02355}, author = {Bhadra, Mohitosh and Sasmal, Himadri Sekhar and Basu, Arghya and Midya, Siba P. and Kandambeth, Sharath and Pachfule, Pradip and Balaraman, Ekambaram and Banerjee, Rahul} } @article {43894, title = {Simple cobalt(II) chloride catalyzed N-alkylation of amines with alcohols}, journal = {Synthesis-Stuttgart }, volume = {49}, year = {2017}, month = {SEP}, pages = {3957-3961}, type = {Journal Article}, chapter = {3957-3961}, abstract = {

A facile cobalt-catalyzed N-alkylation of amines with alcohols using inexpensive, commercially available CoCl2 center dot 6H(2)O is reported. Employing this readily available cobalt catalyst, a variety of amines with wide functional group tolerance were selectively alkylated under benign conditions.

}, keywords = {(Hetero)Aromatic Amines, Alcohols, Amination, amines, Anilines, Aromatic-amines, Cobalt Catalysis, Dehydrogenation Borrowing Hydrogen, Efficient Catalysts, Hydrogen Autotransfer, Iridium, N-alkylation, Pincer-complex, Secondary Alcohols, Selective Alkylation}, issn = {0039-7881}, doi = {10.1055/s-0036-1589064}, author = {Midya, Siba P. and Mondal, Akash and Begum, Ayesha and Balaraman, Ekambaram} } @article {45750, title = {Unified strategy for silver-, base-, and oxidant-free direct arylation of C-H bonds}, journal = {Green Chemistry}, volume = {19}, year = {2017}, month = {MAY }, pages = {2111-2117}, type = {Article}, abstract = {

Here, we report a dual catalytic approach for room temperature direct arylation of C-H bonds with aryldiazonium salts as a simple aryl group donor, also working as an internal oxidant via C-N-2 bond cleavage. This unified strategy has been achieved by the synergistic combination of visible-light metal-free photoredox and palladium catalysis under silver-, base-and/or additive-free conditions. The broad substrate scope, functional group tolerance, excellent regioselectivity and redox-neutral conditions of this process make it attractive for the effective synthesis of a wide range of important N-heterocyclic commodities such as dibenzo [b,d]azepine, carbazole and phenanthridine.

}, issn = {1463-9262}, doi = {10.1039/c6gc03438a}, author = {Sahoo, Manoj K. and Midya, Siba P. and Landge, Vinod G. and Balaraman, Ekambaram} } @article {44227, title = {Cobalt-catalyzed acceptorless dehydrogenative coupling of aminoalcohols with alcohols: direct access to pyrrole, pyridine and pyrazine derivatives}, journal = {Chemical Communications}, volume = {54}, year = {2018}, month = {JAN}, pages = {90-93}, type = {Article}, abstract = {

Here, the first example is reported of a new, molecularly defined SNS-cobalt(II) catalyst for the acceptorless dehydrogenative coupling (ADC) of unprotected amino alcohols with secondary alcohols leading to pyrrole and pyridine derivatives.

}, issn = {1359-7345}, doi = {10.1039/c7cc07427a}, author = {Midya, Siba P. and Landge, Vinod G. and Sahoo, Manoj K. and Rana, Jagannath and Balaraman, Ekambaram} } @article {44615, title = {Direct access to N-alkylated amines and imines via acceptorless dehydrogenative coupling catalyzed by a cobalt(ii)-NNN pincer complex}, journal = {Catalysis Science \& Technology}, volume = {8}, year = {2018}, month = {JUL}, pages = {3469-3473}, abstract = {

A simple, phosphine-free Co(ii)-NNN pincer complex catalyzed direct N-alkylation of anilines with alcohols via hydrogen auto-transfer (HA) and selective acceptorless dehydrogenative coupling (ADC) of benzylamines with alcohols affording imines with the liberation of molecular hydrogen and water is reported.

}, issn = {2044-4753}, doi = {10.1039/c8cy00859k}, author = {Midya, Siba P. and Pitchaimani, Jayaraman and Landge, Vinod G. and Madhu, Vedichi and Balaraman, Ekambaram} } @article {45471, title = { Ni-catalyzed alpha-alkylation of unactivated amides and esters with alcohols by hydrogen auto-transfer strategy }, journal = {CHEMSUSCHEM}, volume = {11}, year = {2018}, month = {NOV}, pages = {3911-3916}, type = {Article}, abstract = {A transition-metal-catalyzed borrowing hydrogen/hydrogen auto-transfer strategy allows the utilization of feedstock alcohols as an alkylating partner, which avoids the formation of stoichiometric salt waste and enables a direct and benign approach for the construction of C-N and C-C bonds. In this study, a nickel-catalyzed alpha-alkylation of unactivated amides and ester (tert-butyl acetate) is carried out by using primary alcohols under mild conditions. This C-C bond-forming reaction is catalyzed by a new, molecularly defined nickel(II) NNN-pincer complex (0.1-1 mol \%) and proceeds through hydrogen auto-transfer, thereby releasing water as the sole byproduct. In addition, N-alkylation of cyclic amides under Ni-catalytic conditions is demonstrated.}, doi = {10.1002/cssc.201801443}, author = {Midya, Siba P. and Rana, Jagannath and Pitchaimani, Jayaraman and Nandakumar, Avanashiappan and Madhu, Vedichi and Balaraman, Ekambaram} } @article {44205, title = {Phosphine-free cobalt pincer complex catalyzed Z-selective semi-hydrogenation of unbiased alkynes}, journal = {Catalysis Science \& Technology}, volume = {8}, year = {2018}, month = {JAN}, pages = {428-433}, type = {Article}, abstract = {

Herein, we report a novel, molecularly defined NNN-type cobalt pincer complex catalyzed transfer semi-hydrogenation of unbiased alkynes to Z-selective alkenes. This unified process is highly stereo-and chemo-selective and exhibits a broad scope as well as wide functional group tolerance. Ammonia-borane (AB), a bench-stable substrate with high gravimetric hydrogen capacity, was used as a safe and practical transfer hydrogenating source.

}, issn = {2044-4753}, doi = {10.1039/c7cy01994g}, author = {Landge, Vinod G. and Pitchaimani, Jayaraman and Midya, Siba P. and Subaramanian, Murugan and Madhu, Vedichi and Balaraman, Ekambaram} } @article {47597, title = {Tandem acceptorless dehydrogenative coupling-decyanation under nickel catalysis}, journal = {Journal of Organic Chemistry}, volume = {86}, year = {2021}, month = {JUN}, pages = {7552-7562}, type = {Article}, abstract = {The development of new catalytic processes based on abundantly available starting materials by cheap metals is always a fascinating task and marks an important transition in the chemical industry. Herein, a nickel-catalyzed acceptorless dehydrogenative coupling of alcohols with nitriles followed by decyanation of nitriles to access diversely substituted olefins is reported. This unprecedented C=C bond-forming methodology takes place in a tandem manner with the formation of formamide as a sole byproduct. The significant advantages of this strategy are the low-cost nickel catalyst, good functional group compatibility (ether, thioether, halo, cyano, ester, amino, N/O/S heterocycles; 43 examples), synthetic convenience, and high reaction selectivity and efficiency.}, issn = {0022-3263}, doi = {10.1021/acs.joc.1c00592}, author = {Midya, Siba P. and Subaramanian, Murugan and Babu, Reshma and Yadav, Vinita and Balaraman, Ekambaram} }