@article { ISI:000329137400042,
	title = {Selective imaging of quorum sensing receptors in bacteria using fluorescent Au nanocluster probes surface functionalized with signal molecules},
	journal = {ACS Applied Materials \& Interfaces},
	volume = {5},
	number = {24},
	year = {2013},
	month = {DEC},
	pages = {13076-13081},
	publisher = {AMER CHEMICAL SOC},
	address = {1155 16TH ST, NW, WASHINGTON, DC 20036 USA},
	abstract = {<p>Fluorescent ultrasmall gold clusters decorated with bacterial quorum sensing signal molecules, acyl homoserine lactone, are synthesized. These fluorescent probes are found to have emission in the near-infrared spectral region advantageous for bioimaging. Imaging studies using different. strains of bacteria with and without acyl homoserine lactone receptors with the aid of confocal microscopy have shown that the probe interacts preferentially with cells possessing these receptors. This indicates that, with appropriate surface functionalization, the Au clusters can be used for receptor specific detection with enhanced selectivity.</p>},
	keywords = {Au nanoclusters, Biosensor, fluorescence imaging, quorum sensing},
	issn = {1944-8244},
	doi = {10.1021/am404093m},
	author = {Mukherji, Ruchira and Samanta, Anupam and Illathvalappil, Rajith and Chowdhury, Somak and Prabhune, Asmita and Devi, R. Nandini}
}
@article {47498,
	title = {Red fluorescent ultra-small gold nanoclusters functionalized with signal molecules to probe specificity in quorum sensing receptors in gram-negative bacteria},
	journal = {Archives of Microbiology},
	year = {2021},
	month = {JUN},
	type = {Article; Early Access},
	abstract = {Ultra-small (size < 2 nm) gold nanoclusters (AuNCs) are used as fluorescent probes which have excellent applications in bioimaging and sensing due to their emission in visible and NIR spectral region. Here, this property is exploited for understanding the quorum sensing phenomenon in bacteria which is regulated by signal molecules which are specific to various species. AuNCs are then functionalized with the signal molecules, Acyl Homoserine Lactones (AHL) of varying carbon chain length, C-6, C-8, and C-12 without 3rd C modification, to sense different strains of gram-negative bacteria i.e., Escherichia coli, Cronobacter sakazakii and Pseudomonas aeruginosa. In the concentration employed, selectivity to a limited extent is observed between the three Gram-negative bacteria tested. E. coli showed emission with all the AHL conjugates and P. aeruginosa did not interact with any of the three conjugates, whereas C. sakazakii showed specificity to C-8AHL. This is probably due to selectivity for cognate AHL molecules of appropriate concentrations.},
	keywords = {acyl homoserine lactone, fluorescence imaging, Gold nanoclusters, quorum sensing, Receptors, selectivity},
	issn = {0302-8933},
	doi = {10.1007/s00203-021-02338-y, Early Access Date = JUN 2021},
	author = {Chahande, Anurag M. and Lathigara, Disha and Prabhune, Asmita A. and Devi, R. Nandini}
}
