@article {43499,
	title = {New and efficient enantioselective synthesis of both enantiomers of the calcium channel blocker bepridil},
	journal = {New Journal of Chemistry},
	volume = {41},
	year = {2017},
	month = {JAN},
	pages = {824-829},
	abstract = {A concise and efficient enantioselective synthesis of both enantiomers of bepridil, a calcium channel blocker, is reported. Jacobsen{\textquoteright}s hydrolytic kinetic resolution method was utilized to resolve racemic 2-(isobutoxymethyl) oxirane. The incorporation of the succinimide moiety by the Mitsunobu reaction, which was investigated in detail, occurred without any loss of enantioselectivity. Using this strategy, both enantiomers of the target molecule were obtained in good yield and with high enantiopurity (ee > 99\%).},
	doi = {10.1039/c6nj02928k},
	author = {Mujahid, Mohammad and Subramanian, Jambu and Nalla, Viswanadh and Sasikumar, Murugesan and Kunte, Sunita Sharad and Muthukrishnan, Murugan}
}
@article {44497,
	title = {Identification of potent chromone embedded [1,2,3]-triazoles as novel anti-tubercular agents},
	journal = {Royal Society Open Science},
	volume = {5},
	year = {2018},
	month = {APR},
	pages = {Article Number: 171750},
	abstract = {A series of 20 novel chromone embedded [1,2,3]-triazoles derivatives were synthesized via an easy and convenient synthetic procedure starting from 2-hydroxy acetophenone. The in vitro anti-mycobacterial evaluation studies carried out in this work reveal that seven compounds exhibit significant inhibition against Mycobacterium tuberculosis H37Rv strain with MIC in the range of 1.56-12.5 mu g ml(-1). Noticeably, compound 6s was the most potent compound in vitro with a MIC value of 1.56 mu g ml(-1). Molecular docking and chemoinformatics studies revealed that compound 6s displayed drug-like properties against the enoyl-acyl carrier protein reductase of M. tuberculosis further establishing its potential as a potent inhibitor.},
	doi = {10.1098/rsos.171750},
	author = {Nalla, Viswanadh and Shaikh, Aslam and Bapat, Sanket and Vyas, Renu and Karthikeyan, M. and Yogeeswari, P. and Sriram, D. and Muthukrishnan, M.}
}
@article {46309,
	title = {New enantioselective synthesis of antiobesity drug lorcaserin},
	journal = {New Journal of Chemistry},
	volume = {43},
	year = {2019},
	month = {NOV },
	pages = {16876-16880},
	type = {Article},
	abstract = {<p>A simple and efficient enantioselective synthesis of anti-obesity drug lorcaerin starting from easily accessible 3-chlorostyrene oxide has been described for the first time employing hydrolytic kinetic resolution as a source of chirality. The protocol might also be useful in the synthesis of structural variants of lorcaserin.</p>
},
	issn = {1144-0546},
	doi = {10.1039/c9nj04234b},
	author = {Ghotekar, Ganesh S. and More, Devidas A. and Nalla, Viswanadh and Muthukrishnan, M.}
}
@article {48909,
	title = {Efficient synthesis of optically active herbicide (S)-metolachlor via reductive ring opening of 2-methoxymethylaziridine},
	journal = {Arkivoc},
	year = {2023},
	month = {JUL},
	type = {Article},
	abstract = {<p>An efficient synthesis of a well known chiral herbicide, (S)-metolachlor has been described using 2methoxymethylaziridine ring formation and reductive ring opening as key steps using commercially available (R)-epichlorohydrin. The present protocol delivers the required enantiomer of metolachlor in overall yield of 50.8\% and high enantiopurity (\&gt;99\%).</p>
},
	keywords = {Aziridine, Epoxide, Epoxide ring opening, herbicide synthesis, Metolachlor},
	issn = {1551-7004},
	doi = {10.24820/ark.5550190.p011.954},
	author = {Nalla, Viswanadh and Mujahid, Mohammad and Sasikumar, Murugesan and Mujumdar, Prashant and Muthukrishnan, Murugan}
}
