@article { ISI:000358099300015, title = {Enantioselective synthesis of (+)-hygroline and (+)-pseudohygroline via Keck allylation and CBS reduction}, journal = {Tetrahedron Letters}, volume = {56}, number = {32}, year = {2015}, month = {AUG}, pages = {4704-4705}, publisher = {PERGAMON-ELSEVIER SCIENCE LTD}, address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND}, abstract = {

An enantioselective synthesis of (+)-hygroline and (+)-pseudohygroline has been achieved in high optical purity (98\% ee) from readily available 1,4-butanediol. The synthesis strategy employs a Keck allylation, CBS reduction, and Wacker oxidation. (C) 2015 Elsevier Ltd. All rights reserved.

}, keywords = {CBS reduction, Keck allylation, Pyrrolidines, Wacker oxidation}, issn = {0040-4039}, doi = {10.1016/j.tetlet.2015.06.012}, author = {Bhoite, Shubhangi P. and Kamble, Rohit B. and Suryavanshi, Gurunath M.} } @article { ISI:000350528300022, title = {Formal asymmetric synthesis of (2S,4R)-4-hydroxypipecolic acid via Co(III)(salen)-catalyzed two stereocentered HKR of racemic azido epoxide}, journal = {Tetrahedron Letters}, volume = {56}, number = {10}, year = {2015}, month = {MAR}, pages = {1263-1265}, publisher = {PERGAMON-ELSEVIER SCIENCE LTD}, address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND}, abstract = {

An efficient formal synthesis of (2S,4R)-4-hydroxypipecolic acid has been achieved in high optical purity (99\% ee) from readily available benzaldehyde. The strategy employs an iodine-induced intramolecular cyclization of a carbonate and Co-catalyzed Hydrolytic Kinetic Resolution (HKR) of two stereocentered racemic azido epoxide as the key reactions to construct chiral 1,3-amino alcohol functionality. (C) 2015 Elsevier Ltd. All rights reserved.

}, keywords = {Azido epoxide, Hydrolytic kinetic resolution, lodocyclization, Piperidine}, issn = {0040-4039}, doi = {10.1016/j.tetlet.2015.01.113}, author = {Kamble, Rohit B. and Gadre, Shubhankar Haribhau and Suryavanshi, Gurunath M.} } @article {44524, title = {Metal-free annulation of β-acylamino ketones: facile access to spirooxazolines and oxazolines via oxidative C{\textendash}O bond formation}, journal = {Organic Chemistry Frontiers }, volume = {5}, year = {2018}, month = {OCT}, pages = {544-548 }, abstract = {A metal-free annulation reaction of β-acylamino ketone derivatives has been reported for the synthesis of a group of functionalized spirooxazolines and oxazolines in good to excellent yields. The reaction proceeds via phenyliodine(III) diacetate (PIDA)-mediated oxidative C{\textendash}O bond formation in the presence of BF3{\textendash}OEt2. The mild reaction conditions, broad substrate scope, simple execution and synthetic potential of the products make this novel protocol very attractive.}, doi = {10.1039/C7QO00783C}, author = {Chavan, Santosh S. and Rupanawar, Bapurao D. and Kamble, Rohit B. and Shelke, Anil M. and Gurunath Suryavanshi} } @article {44502, title = {Synthesis of key intermediate for (+)-tofacitinib through CoIII(salen)-catalyzed two stereocentered hydrolytic kinetic resolution of ({\^A}{\textpm})-methyl-3-(oxiran-2-yl)butanoate}, journal = { Synthetic Communications}, volume = {48}, year = {2018}, month = {MAR}, pages = {1045-1051}, type = {Journal Article}, abstract = {An enantiopure piperidine, a key intermediate for the synthesis of (+)-tofacitinib, has been achieved in high optical purity (98\% ee) from readily available crotyl alcohol. The key steps involved is a CoIII(salen)-OAc-catalyzed two stereocentered hydrolytic kinetic resolution of ({\textpm})-methyl-3-(oxiran-2-yl)butanoate.}, keywords = {enantioselective, Hydrolytic kinetic resolution, iodolactonization, γ-Butyralactone}, issn = {397911}, doi = {10.1080/00397911.2018.1434204}, author = {Kamble, Rohit B.}, editor = {Suryavanshi, Gurunath} } @article {44442, title = {Two stereocentered HKR of anti-β,β'-diphenylpropanoxirane and anti-3-phenylethyloxiranes catalysed by Co(III)(salen)-OAc complex: enantioselective synthesis of (+)-sertraline and (+)-naproxen}, journal = {New Journal of Chemistry}, volume = {42}, year = {2018}, month = {May 2018}, pages = {10414-10420}, type = {Journal Article}, abstract = {

The Co(III)(salen)OAc-catalyzed two stereocentered hydrolytic kinetic resolution (HKR) of anti-β,β'-diphenylmethyloxirane and anti-3-phenylethyloxiranes affords the corresponding anti-1,2-diols and oxiranes in high enantiomeric excess. The synthetic potential of this methodology is demonstrated by the enantioselective synthesis of (+)-sertraline, an antidepressant drug, and (+)-naproxen, an anti-inflammatory drug.

}, issn = {11440546}, doi = {10.1039/c8nj01616j}, author = {Kamble, Rohit B.}, editor = {Devalankar, Dattatraya} } @article {46102, title = {Visible light mediated, metal and oxidant free highly efficient cross dehydrogenative coupling (CDC) reaction between quinoxalin-2(1H)-ones and ethers}, journal = {New Journal of Chemistry}, volume = {43}, year = {2019}, month = {MAY}, pages = {7403-7408}, type = {Article}, abstract = {

The efficient and metal free, white light mediated 3C alkylation of quinoxalin-2(1H)-ones via a cross dehydrogenative coupling reaction with cyclic ethers using eosin Y as a photocatalyst is described. This reaction has broad substrate scope and strong functional group tolerance with good to excellent yields.

}, issn = {1144-0546}, doi = {10.1039/c9nj00075e}, author = {Mane, Kishor D. and Kamble, Rohit B. and Suryavanshi, Gurunath} } @article {47008, title = {Ti-superoxide catalyzed oxidative amidation of aldehydes with saccharin as nitrogen source: synthesis of primary amides}, journal = {RSC Advances}, volume = {10}, year = {2020}, month = {JAN}, pages = {724-728}, type = {Article}, abstract = {

A new heterogeneous catalytic system (Ti-superoxide/saccharin/TBHP) has been developed that efficiently catalyzes oxidative amidation of aldehydes to produce various primary amides. The protocol employs saccharin as amine source and was found to tolerate a wide range of substrates with different functional groups. Moderate to excellent yields, catalyst reusability and operational simplicity are the main highlights. A possible mechanism and the role of the catalyst in oxidative amidation have also been discussed.

}, doi = {10.1039/c9ra10413e}, author = {Kamble, Rohit B. and Mane, Kishor D. and Rupanawar, Bapurao D. and Korekar, Pranjal and Sudalai, A. and Suryavanshi, Gurunath} } @article {47080, title = {Oxidative radical-mediated addition of ethers to quinone imine ketals: an access to hemiaminals}, journal = {Journal of Organic Chemistry}, volume = {86}, year = {2021}, month = {FEB }, pages = {2107-2116}, type = {Article}, abstract = {

The highly regioselective synthesis of substituted hemiaminal via addition of ethers to quinone imine ketals (QIKs) has been developed under metal-free conditions. In the presence of tetrabutylammonium chloride and potassium persulfate (K2S2O8), QIKs couple efficiently with cyclic and acyclic ethers to give hemiaminals. This strategy offers an easy access to substituted hemiaminal ethers with high functional group tolerance in good to excellent yields.

}, issn = {0022-3263}, doi = {10.1021/acs.joc.0c02254}, author = {More, Satish G. and Kamble, Rohit B. and Suryavanshi, Gurunath} } @article {47427, title = {Short enantioselective total synthesis of (+)-tofacitinib}, journal = {Tetrahedron Letters}, volume = {67}, year = {2021}, month = {MAR}, pages = {152838}, type = {Article}, abstract = {

An enantioselective total synthesis of Tofacitinib (CP-690,550), a Janus tyrosine kinase (JAK3) specific inhibitor has been achieved from the readily available 4-piperidone. Proline catalysed hydroxylation is the key step for the synthesis of enantiopure 1-benzyl-4-methylpiperidin-3-ol. (C) 2021 Elsevier Ltd. All rights reserved.

}, keywords = {aminohydroxylation, Hydrogenation, L-proline, piperidone}, issn = {0040-4039}, doi = {10.1016/j.tetlet.2021.152838}, author = {Mane, Kishor D. and Kamble, Rohit B. and Suryavanshi, Gurunath} }