@article {50127,
	title = {One-pot synthesis of N-arylated benzotriazoles and benzotriazinones via in situ diazotization and aryne trapping},
	journal = {Organic \& Biomolecular Chemistry},
	volume = {24},
	year = {2026},
	month = {JUN},
	pages = {4696-4711},
	type = {Article},
	abstract = {<p>
	N-Arylated benzotriazoles and 1,2,3-benzotriazin-4-ones are important structural motifs in synthetic and medicinal chemistry, valued for their distinctive frameworks and functional versatility. We have developed an efficient, one-pot strategy for the synthesis of N-arylated benzotriazoles and benzotriazinones. The protocol involves in situ diazotization of o-phenylenediamine or 2-aminobenzamide using tert-butyl nitrite (tBuONO), followed by trapping of arynes generated in situ from 2-(trimethylsilyl)aryltriflates in the presence of CsF. The methodology exhibits broad functional-group tolerance and was successfully applied to 47 substrates, affording yields in the range of 60-85\%. Furthermore, gram-scale synthesis highlights the operational simplicity and practical utility of this approach.</p>
},
	issn = {1477-0520},
	doi = {10.1039/d6ob00648e},
	author = {Ghodake, Balaji M. and Bhattacharya, Asish K.}
}
