@article {49916,
	title = {NHC/Phosphite Nickel(II) Precatalysts for the C-N Cross-Coupling of (Hetero)Aryl Chlorides under Mild Conditions},
	journal = {ORGANIC LETTERS},
	volume = {27},
	year = {2025},
	month = {SEP },
	pages = {10526-10531},
	type = {Article},
	abstract = {<p>
	We report the synthesis of three nickel complexes based on Ni(NHC)[P(OR)3](Ar)Cl and their application in C(sp 2)-N cross-coupling reactions. Reactions involving secondary amines proceeded at room temperature, while anilines and primary alkyl amines coupled under mild heating. The reported complexes are air-stable as solids, operate at low catalytic loading, and do not require an exogenous ligand. Mechanistic studies suggest both free and Ni-bound phosphite are present during the reaction and that an isolated [Ni(NHC)(amine)(Ar)Cl] complex could be an on-cycle, catalytically active species.</p>
},
	issn = {1523-7060},
	doi = {10.1021/acs.orglett.5c03230},
	author = {Darandale, Nutan R. and John, Morgan E. and Moggach, Stephen A. and Sawant, Dinesh N. and Koutsantonis, George A. and Dorta, Reto and Stewart, Scott G.}
}
