@article {49832,
	title = {Base mediated approach for the synthesis of deoxybenzoins using γ-aryl-β-ketoesters and benzoyl chlorides},
	journal = {RSC Advances},
	volume = {15},
	year = {2025},
	month = {SEP },
	pages = {32424-32430},
	type = {Article},
	abstract = {<p>
	This study introduces a one-pot, transition metal-free strategy for synthesizing deoxybenzoins, overcoming the challenges of conventional methods. The reaction involves dual acylation of gamma-aryl beta-keto esters using K2CO3 in dioxane at 90 degrees C, followed by a concerted transformation to form deoxybenzoin. The protocol operates under mild conditions, tolerates a broad range of substrates, and produces minimal by-products, making it a practical, scalable alternative for accessing pharmaceutically relevant deoxybenzoins.</p>
},
	doi = {10.1039/d5ra05242d},
	author = {Choudhary, Shailendra Singh and Darole, Ratanamala S. and Krishna, Gamidi Rama and Senthilkumar, Beeran}
}
