@article {49604,
	title = {AgOTf-catalyzed cascade annulation of 5-hexyn-1-ols and aldehydes: enabling the diastereoselective synthesis of [6,6,6]-trioxa-fused ketals and hexahydro-2H-chromenes},
	journal = {Chemical Communications},
	volume = {61},
	year = {2025},
	month = {JAN },
	pages = {973-976},
	type = {Article},
	abstract = {<p>
	We report the unprecedented diastereoselective synthesis of novel [6,6,6]-trioxa-fused ketals via AgOTf-catalyzed cascade annulation of 5-hexyn-1-ols (with primary or secondary hydroxyl groups) and aldehydes through a [2+2+1+1] pathway. In contrast, 5-hexyn-1-ols with tertiary hydroxyl groups yield hexahydro-2H-chromenes via a [3+1+1+1] pathway.</p>
},
	issn = {1359-7345},
	doi = {10.1039/d4cc05546b},
	author = {Vinodkumar, Ramavath and Nakate, Ashwini K. and Krishna, Gamidi Rama and Kontham, Ravindar}
}
