@article {49309,
	title = {Highly selective C-N and C-S dual functionalization of 1,3-dicarbonyl derivatives using TBHP as an oxidant},
	journal = {Journal of Organic Chemistry},
	volume = {89},
	year = {2024},
	month = {JUN},
	pages = {9371-9380},
	type = {Article},
	abstract = {<p>
	A direct electrosynthesis/photocatalyst-free, atom-economical, and efficient method for the selective synthesis of (E)-3-amino-2-thiocyanato-alpha,beta-unsaturated carbonyl compounds is described through a given protocol. The present approach features the use of inexpensive ammonium thiocyanate to achieve dual functionalization of 1,3-dicarbonyl compounds using TBHP as an oxidant, providing a rapid and practical route to the selective formation of both C-N and C-S bonds via a radical process. This method offers a broad substrate scope with excellent yield and allows for further exploration of the products to construct heterocyclic compounds and other functionalities.</p>
},
	issn = {0022-3263},
	doi = {10.1021/acs.joc.4c00612},
	author = {Bagad, Pooja K. and Darole, Ratanamala S. and Krishna, G. Rama and Senthilkumar, Beeran}
}
