@article {49252,
	title = {One-pot synthesis of pyrazoles from sulfonyl hydrazides and alkynyl ketones using environmentally benign sulfonium iodate (I) reagent},
	journal = {ChemistrySelect},
	volume = {9},
	year = {2024},
	month = {OCT},
	pages = {e202403249},
	type = {Article},
	abstract = {<p>
	Pyrazole is an omnipresent moiety in many natural products and pharmaceutically active compounds. Here, we have developed a simple and dynamic method for one-pot synthesis of substituted pyrazoles through the intramolecular cyclization of hydrazides and alkynyl ketones, using a novel sulfonium saltbased iodate (\&amp; Iukcy;) reagent system. This method has the advantage that it proceeds in a one-pot, without isolating a less stable hydrazone intermediate. Hypervalent iodine-based reagents are an environmentally benign and greener option to toxic metal oxidants; they have an extensive application in metal-catalyst-free reactions, and this reaction proceeds in less time with high yields.</p>
},
	keywords = {Deprotonation, One-pot reaction, Oxidative iodination, Pyrazole, S(N)2-type cyclization},
	issn = {2365-6549},
	doi = {10.1002/slct.202403249},
	author = {Mishra, Akanksha and Talukdar, Mrinal and Krishna, Gamidi Rama and Begari, Eeshwaraiah}
}
