@article {49104,
	title = {Article chitinase inhibition induces transcriptional dysregulation altering ecdysteroid-mediated control of spodoptera frugiperda development},
	journal = {Iscience},
	volume = {27},
	year = {2024},
	month = {MAR },
	type = {Article},
	abstract = {<p>
	Chitinases and ecdysteroid hormones are vital for insect development. Crosstalk between chitin and ecdysteroid metabolism regulation is enigmatic. Here, we examined chitinase inhibition effect on Spodopsilencing and overexpression resulted in ecdysone receptor deregulation. Transcription factors, like Neverland, and other ecdysteroid biosynthesis genes might lead to their upregulation in berberine-fed chitinase activity{\textquoteright}s impact on ecdysone biosynthesis and its transcriptional crosstalk.</p>
},
	doi = {10.1016/j.isci.2024.109280},
	author = {Barbole, Ranjit S. and Sharma, Shivani and Patil, Yogita and Giri, Ashok P. and Joshi, Rakesh S.}
}
