@article {48909,
	title = {Efficient synthesis of optically active herbicide (S)-metolachlor via reductive ring opening of 2-methoxymethylaziridine},
	journal = {Arkivoc},
	year = {2023},
	month = {JUL},
	type = {Article},
	abstract = {<p>An efficient synthesis of a well known chiral herbicide, (S)-metolachlor has been described using 2methoxymethylaziridine ring formation and reductive ring opening as key steps using commercially available (R)-epichlorohydrin. The present protocol delivers the required enantiomer of metolachlor in overall yield of 50.8\% and high enantiopurity (\&gt;99\%).</p>
},
	keywords = {Aziridine, Epoxide, Epoxide ring opening, herbicide synthesis, Metolachlor},
	issn = {1551-7004},
	doi = {10.24820/ark.5550190.p011.954},
	author = {Nalla, Viswanadh and Mujahid, Mohammad and Sasikumar, Murugesan and Mujumdar, Prashant and Muthukrishnan, Murugan}
}
