@article {48801,
	title = {Total synthesis and absolute configuration determination of the α-glycosidase inhibitor (3S,4R)-6-Acetyl-3-hydroxy-2,2-dimethylchroman-4-yl (Z)-2-Methylbut-2-enoate from Ageratina grandifolia},
	journal = {Journal of Natural Products},
	volume = {86},
	year = {2023},
	month = {JUN},
	pages = {1878-1883},
	type = {Article},
	abstract = {<p>
	Herein, we report the first total synthesis of \&amp; alpha;-glycosidaseinhibitor (3R, 4S)-6-acetyl-3-hydroxy-2,2-dimethylchroman-4-yl(Z)-2-methylbut-2-enoate as well as its enantiomer.Our synthesis confirms the chromane structure separately proposedby Navarro-Vazquez and Mata, on the basis of DFT computations. Furthermore,our synthesis allowed us to determine the absolute configuration ofthe natural compound as (3S, 4R)and not (3R, 4S).</p>
},
	issn = {0163-3864},
	doi = {10.1021/acs.jnatprod.3c00236},
	author = {Dandawate, Monica and Choudhury, Rahul and Krishna, Gamidi Rama and Reddy, D. Srinivasa}
}
