@article {48709,
	title = {Bi(III)-catalyzed synthesis of substituted furans from hydroxy-oxetanyl ketones: application to unified total synthesis of shikonofurans J, D, E, and C},
	journal = {Journal of Organic Chemistry},
	volume = {88},
	year = {2023},
	month = {MAY},
	pages = {7328-7346},
	type = {Article},
	abstract = {<p>
	We report an improved synthetic protocol for hydroxymethyl-derivedpolysubstituted furans employing Bi-(III)-catalyzed dehydrative cycloisomerizationof alpha-hydroxy oxetanyl ketones. This procedure provides rapidaccess (within 5 min) to highly substituted furans with exceptionalfunctional group diversity, excellent yields, generality, scalability,and operationally simple reaction conditions. Further, it demonstratedthe utility of this method in the first enantioselective total synthesisof furyl-hydroquinone-derived biologically potent natural productsshikonofurans J, D, E, and C in seven linear steps, starting fromreadily available building blocks of 2,5-dihydroxy acetophenone and3-oxetanone employing chiral-phosphoric acid (TRIP)-catalyzed asymmetricprenylation as a key step to induce the chirality.</p>
},
	issn = {0022-3263},
	doi = {10.1021/acs.joc.3c00549},
	author = {Kataria, Priyanka and Sahoo, Shubhranshu Shekhar and Kontham, Ravindar}
}
