@article {48066,
	title = {Lewis acid triggered N-alkylation of sulfoximines through nucleophilic ring-opening of donor-acceptor cyclopropanes: synthesis of gamma-sulfoximino malonic diesters},
	journal = {Organic \& Biomolecular Chemistry},
	volume = {20},
	year = {2022},
	month = {MAR },
	pages = {2518-2529},
	type = {Article},
	abstract = {<p>
	Scandium triflate (Sc(OTf)(3)) catalyzed, mild, and regioselective ring-opening reaction of donor-acceptor (D-A) cyclopropanes has been developed using sulfoximines for the synthesis of gamma-sulfoximino malonic diesters. This protocol allows the synthesis of different N-alkyl sulfoximines in good to excellent yields (up to 94\%) with broad functional group tolerance. In this process, N-H and C-C bonds are cleaved to form new C-N and C-H bonds. The feasibility of this method is supported by a gram-scale reaction and synthetic elaboration of the obtained product.</p>
},
	issn = {1477-0520},
	doi = {10.1039/d2ob00213b},
	author = {More, Satish G. and Suryavanshi, Gurunath}
}
