@article {47626,
	title = {Enantioselective synthesis of 5,6-dihydroindolizines by N-heterocyclic carbene (NHC)-catalyzed core-structure-inspired strategy of azolium-enolate cascade},
	journal = {Organic Letters},
	volume = {23},
	year = {2021},
	month = {JUL },
	pages = {5223-5228},
	type = {Article},
	abstract = {The core-structure motivated design has allowed the enantioselective synthesis of 5,6-dihydroindolizines via N-heterocyclic carbene (NHC) catalysis. The NHC-catalyzed reaction of alpha,beta-unsaturated aldehydes with the suitably substituted pyrrole derivatives proceed via the initial generation of alpha,beta-unsaturated acylazoliums from enals, and enolates from pyrroles and the reaction culminated in an efficient cascade process involving the Michael-aldol-lactonization-decarboxylation sequence to afford the products in reasonable yields and high selectivities. The method is further extended to the construction of spirocyclic 5,6-dihydroindolizines.},
	issn = {1523-7060},
	doi = {10.1021/acs.orglett.1c01761},
	author = {Ghosh, Arghya and Shee, Sayan and Barik, Shilpa and Gonnade, Rajesh G. and Biju, Akkattu T.}
}
