@article {47383,
	title = {Concise/catalytic approach for the construction of the C14-C28 fragment of eribulin},
	journal = {Organic \& Biomolecular Chemistry},
	volume = {19},
	year = {2021},
	month = {MAY},
	pages = {4542-4550},
	type = {Article},
	abstract = {<p>A simple approach for the synthesis of the C14-C28 fragment of eribulin has been developed by employing a one-pot gold-catalyzed alkynol cyclization/Kishi reduction to construct the 1,5-cis-tetrahydropyran unit and a cross-metathesis/Sharpless asymmetric dihydroxylation-cycloetherification to install the 1,4-trans-tetrahydrofuran ring. Use of easily accessible building blocks, ease of operation and catalytic transformations as key reactions for the construction of THF/THP units highlight the current approach.</p>},
	issn = {1477-0520},
	doi = {10.1039/d1ob00661d, Early Access Date = APR 2021},
	author = {Senapati, Sibadatta and Ramana, V, Chepuri}
}
