@article {47025,
	title = {Short review of synthetic routes for the antiepileptic drug (R)-lacosamide},
	journal = {Organic Process Research \& Development},
	volume = {24},
	year = {2020},
	month = {JAN},
	pages = {17-24},
	type = {Review},
	abstract = {<p>The disease epilepsy affects people of all ages and is due to a chronic neurological disorder in the brain. According to a report by the World Health Organization, epilepsy is one of the most common global neurological diseases. (R)-Lacosamide (Vimpat) was introduced by UCB Pharma in 2008 for the treatment of partial-onset seizures in patients suffering from epilepsy. This review summarizes all of the available synthetic strategies reported for (R)-lacosamide, which will help medicinal chemists in the further development of its synthesis.</p>
},
	keywords = {antiepileptic drug, epilepsy, lacosamide, serine derivative, synthesis},
	issn = {1083-6160},
	doi = {10.1021/acs.oprd.9b00373},
	author = {Aratikatla, Eswar K. and Bhattacharya, Asish K.}
}
