@article {46993,
	title = {Manganese-catalyzed alpha-olefination of nitriles with secondary alcohols},
	journal = {ACS Catalysis},
	volume = {10},
	year = {2020},
	month = {JAN},
	pages = {947-954},
	type = {Article},
	abstract = {<p>An expedient catalytic approach for alpha-olefination of nitriles using secondary alcohols with the liberation of molecular hydrogen and water as the only byproducts is reported. This reaction is catalyzed by a molecularly defined manganese(I) pincer complex and operates in the absence of any hydrogen acceptors. A broad range of substrates including cyclic, acyclic, and benzylic alcohols, as well as various nitrile derivatives, such as arylmethyl and heteroarylmethyl nitriles, are employed in the reaction to provide a diverse range of alpha-vinyl nitriles in good to excellent yields. Mechanistic studies showed that the reaction proceeds via dehydrogenative pathway and the activation of alpha(C-H) bond of the alcohol is the rate-determining step.</p>
},
	keywords = {acceptorless dehydrogenation, Alcohol, alpha-olefination, Hydrogen, manganese},
	issn = {2155-5435},
	doi = {10.1021/acscatal.9b02811},
	author = {Yadav, Vinita and Landge, Vinod G. and Subaramanian, Murugan and Balaraman, Ekambaram}
}
