@article {46818,
	title = {MnBr2-catalyzed direct and site-selective alkylation of indoles and benzo[h]quinoline},
	journal = {Organic Letters},
	volume = {22},
	year = {2020},
	month = {JUN},
	pages = {4643-4647},
	type = {Article},
	abstract = {<p>Manganese-catalyzed regioselective C-H alkylation of indoles and benzo[h]quinoline with a variety of unactivated alkyl iodides is reported. Unlike other Mn-catalyzed C-H functionalization, this protocol does not require a Grignard reagent base and employs a simple and inexpensive MnBr2 as a catalyst. This method tolerates diverse functionalities, including fluoro, chloro, bromo, iodo, alkenyl, alkynyl, pyrrolyl, and carbazolyl groups. The alkylation proceeds through a single-electron transfer pathway comprising reversible C-H manganesation and involving an alkyl radical intermediate.</p>
},
	issn = {1523-7060},
	doi = {10.1021/acs.orglett.0c01398},
	author = {Jagtap, Rahul A. and Verma, Suryadev K. and Punji, Benudhar}
}
