@article {46434,
	title = {Chiral separation of styrene oxides supported by enantiomeric tetrahedral neutral Pd(II) cages},
	journal = {Inorganic Chemistry},
	volume = {58},
	year = {2019},
	month = {NOV},
	pages = {15017-15020},
	type = {Article},
	abstract = {<p>The separation of enantiomers is of considerable importance in the preparation of the compounds of biological interests, catalysis, and drug development. Here, we report a novel enantioseparation of styrene epoxides (SOs) resolved in the presence of a pair of enantio-enriched tetrahedral cages. Chiral neutral cages of formula [(Pd3X*)(4)(C6O4Cl2)(6)] ([X*](3-) = RRR-or SSS-[PO(N(*CH(CH3)Ph)(3)](3)) are constructed from Pcl, building units supported by tris(imido)phosphate trianions and chloranilate linkers. These cages exhibit considerable enantioselective separation capabilities toward a series of styrene epoxides via a crystallization inclusion method. A highest enantiomeric excess (ee) value of up to 80\% is achieved for the (R)-4-fluorostyrene oxide.</p>
},
	issn = {0020-1669},
	doi = {10.1021/acs.inorgchem.9b02389},
	author = {Rajasekar, Prabhakaran and Pandey, Swechchha and Ferrara, Joseph D. and Del Campo, Mark and Le Magueres, Pierre and Boomishankar, Ramamoorthy}
}
