@article {45932,
	title = {Concise enantioselective synthesis of (2S,3S)-3-hydroxypipecolic acid via proline catalyzed alpha-aminooxylation of aldehydes and Pd-catalyzed ether directed aza-Claisen rearrangements},
	journal = {Tetrahedron-Asymmetry},
	volume = {26},
	year = {2015},
	month = {JAN },
	pages = {24-28},
	type = {Article},
	abstract = {<p>An efficient approach to (2S,3S)-3-hydroxypipecolic acid with an overall yield of 10.2\% and 98\% ee starting from 1,5-pentanediol has been developed. The key steps employed in the synthesis are the D-proline catalyzed sequential alpha-aminooxylation/Horner-Wadsworth-Emmons olefination of an aldehyde and the Pd-catalyzed MOM-ether directed aza-Claisen rearrangement of an allylic trichloroacetimidate. (C) 2014 Elsevier Ltd. All rights reserved.</p>},
	issn = {0957-4166},
	doi = {10.1016/j.tetasy.2014.11.010},
	author = {Ahuja, Brij Bhushan and Sudalai, Arumugam}
}
