@article {45463,
	title = {Recent advances in the organocatalytic enantioselective synthesis of functionalized -lactones},
	journal = {Chemistry-An Asian Journal},
	volume = {13  },
	year = {2018},
	month = {SEP},
	pages = {2333-2349 },
	type = {Article},
	abstract = {<p>This Focus Review highlights recent developments in the organocatalytic enantioselective synthesis of -lactone derivatives. Owing to the importance of -lactones as a heterocyclic motif that is present in a variety of natural products and biologically active molecules, several catalytic methods have been developed for the synthesis of these compounds in their enantiomerically pure form. Organocatalytic methods that employ N-heterocyclic carbenes (NHCs), cinchona alkaloids, isothioureas, 4-dimethylaminopyridine (DMAP) derivatives, and phosphines have allowed the highly enantioselective synthesis of -lactones from cheap and readily available starting materials. Moreover, the inherent strain in the four-membered ring of -lactones has also been utilized in further synthetic transformations, thus making -lactones a versatile intermediate in organic synthesis.</p>},
	doi = {10.1002/asia.201800902},
	author = {Mukherjee, Subrata and Biju, Akkattu T.}
}
