@article {45426,
	title = { Regioselective and stereoselective reductive aziridinium ring cleavage leading to azabicyclodecane architecture: enantioselective synthesis of (+)-subincanadine F},
	journal = {Journal of Organic Chemistry},
	volume = {83},
	year = {2018},
	month = {OCT},
	pages = {12164-12170},
	type = {Article},
	abstract = {Enantioselective synthesis of cytotoxic indole alkaloid (+)-subincanadine F was accomplished starting from the corresponding (S)-acetoxysuccinimide via aziridinium ring formation and its reductive ring expansion route. Regioselective and stereoselective reductive aziridinium carbon-nitrogen bond cleavage comprising ring expansions was a key step. The (S)-OMOM protection of the hydroxyl moiety adjacent to a benzylic carbon of an in situ formed aziridinium system was necessary for lithium borohydride-induced reductive ring expansions, and it also served as a latent source of an essential ketone carbonyl group for the generation of an alpha,beta-conjugated system.},
	issn = { 0022-3263},
	doi = {10.1021/acs.joc.8b02113},
	author = {Kalshetti, Manojkumar G. and Argade, Narshinha P.}
}
