@article {44631,
	title = {Four-step total synthesis of (+)-yaoshanenolides A and B},
	journal = {ACS Omega},
	volume = {3},
	year = {2018},
	month = {JUN},
	pages = {7036-7045},
	abstract = {<p>A highly concise bioinspired four-step total synthesis of yaoshanenolides A and B possessing tricyclic spirolactone with an unusual 5{\textquoteright}H-spiro-[bicyclo[2.2.2]-oct[2] ene-7,2{\textquoteright}-furan]-5{\textquoteright}-one scaffold is reported. This synthesis features high-yielding aldol-type addition of gamma-butyrolactone on to the aldehyde, exocyclic olefination of lactone derivative using Eschenmoser{\textquoteright}s salt, and highly facial-and endo-selective [4 + 2]-cycloaddition of fully functionalized 5-methylene-2(5H)-furanone with natural R-(-)-alpha-phellandrene. The approach allows access to yaoshanenolides A and B in four linear steps in 11 and 13\% overall yield.</p>},
	issn = {2470-1343},
	doi = {10.1021/acsomega.8b00701},
	author = {Thorat, Sagar S. and Palange, Megha N. and Kontham, Ravindar}
}
