@article {43815,
	title = {Synthesis of meta-substituted monodentate phosphinite ligands and implication in hydroformylation},
	journal = {Journal of Chemical Sciences},
	volume = {129},
	year = {2017},
	month = {AUG},
	pages = {1143-1152},
	type = {Article},
	abstract = {Synthesis of meta-substituted phosphinite ligands 3,3{\textquoteright}-(methoxyphosphanediyl) bis(N, N-diethylaniline) (4a) and methoxybis(3-methoxyphenyl) phosphane (4b), in high yields, has been demonstrated. Typical phosphorus chemical shift between 110-120 ppm, appearance of methoxy protons and corresponding carbon, as well as ESI-MS spectra unambiguously confirmed the existence of phosphinite ligands 4a and 4b. To demonstrate the synthetic usefulness of 4a and 4b, these ligands were tested in the rhodium catalyzed hydroformylation of 1-octene. The diethylamine substituted ligand 4a was found to be highly active, whereas 4bwas less reactive but revealed slightly better regioselectivity of 62\% under optimized conditions. Additionally, 4a and 4b were found to catalyze the hydroformylation of styrene, 1-undecenol and 1,1-disubstituted functional olefin, methyl methacrylate. Both the ligands displayed excellent conversion of styrene, and 4b revealed an excellent branch selectivity of 75\%. Although 1-undecenol proved to be amenable to hydroformylation (85-90\% conversion to aldehyde), both the ligands failed to discriminate between the linear and branched products. Substrate methyl methacrylate proved to be highly challenging and reduced conversion (between 33-42\%) was observed under optimized conditions. Ligand 4a was found to be highly selective towards linear aldehyde (81\% linear selectivity).},
	doi = {10.1007/s12039-017-1341-z},
	author = {Deshmukh, Satej S. and Gaikwad, Shahaji R. and Pandey, Swechchha and Mali, Pramod S. and Chikkali, Samir H.}
}
