@article {42693,
	title = {Expedient cobalt-catalyzed C{\textendash}H alkynylation of (enantiopure) benzylamines},
	journal = {Organic Letters},
	volume = {18},
	year = {2016},
	month = {OCT},
	pages = {5252-5255},
	abstract = {<p>A unified strategy for cobalt-catalyzed ortho-C-H bond alkynylation of benzylamines is reported. Simple, commercially available CoBr2 was used as a cobalt source. The developed alkynylation strategy is robust and efficient and has a broad substrate scope including 1 degrees, 2 degrees, and 3 degrees benzylamines. The mechanistic study shows that C-H bond cleavage is reversible, and the kinetic study illustrates that the rate of reaction depends solely on the catalyst.</p>},
	keywords = {Terminal Alkynes; Bond Activation; Directed Functionalization;Aminoquinoline Benzamides; Ortho-C(Sp(2))-H Bonds; Mechanistic Insights; Selective Access; Carbon-Hydrogen; Nickel; Annulation},
	doi = {10.1021/acs.orglett.6b02549},
	author = {Landge, Vinod Gokulkrishna and Midya, Siba Prasad and Rana, Jagannath and Shinde, Dinesh R. and Balaraman, Ekambaram}
}
