@article {42430,
	title = {Selective synthesis of N-unsubstituted and N-arylindoles by the reaction of arynes with azirines},
	journal = {Journal of Organic Chemistry},
	volume = {81},
	year = {2016},
	month = {SEP},
	pages = {8604-8611},
	abstract = {<p><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; background-color: rgb(248, 248, 248);">The transition-metal-free and temperature-dependent highly selective reaction of arynes with 2H-azirines allowing the synthesis of either N-unsubstituted or N-arylindoles has been developed. At 60 degrees C, arynes generated from 2-(trimethylsilyl)aryl triflates smoothly insert into 2H-azirines to form 2,3-diarylindoles with high selectivity. Interestingly, when the reaction was performed at -10 degrees C, the selectivity was switched to the formation of 1,2,3-triarylindoles in good yields.</span></p>},
	doi = {10.1021/acs.joc.6b01472},
	author = {Thangaraj, Manikandan and Bhojgude, Sachin Suresh and "Jain, Shailja" and Gonnade, Rajesh G. and Biju, Akkattu T.}
}
