@article { ISI:000244470700005,
	title = {Asymmetric synthesis of (R)-(-)-baclofen via asymmetric dihydroxylation},
	journal = {Indian Journal of Chemistry Section B-Organic Chemistry including Medicinal Chemistry},
	volume = {46},
	number = {2},
	year = {2007},
	month = {FEB},
	pages = {326-330},
	publisher = {NATL INST SCIENCE COMMUNICATION},
	type = {Article},
	address = {DR K S KRISHNAN MARG, NEW DELHI 110 012, INDIA},
	abstract = {<p>A short and efficient asymmetric synthesis of (R)-(-)-baclofen, a selective GABA(B) agonist has been described with an overall yield of 14\% and 85\% ee. The Os-catalyzed Sharpless asymmetric dihydroxylation of alpha,beta-unsaturated olefin constitutes the key step in introducing stereogenic centers into the molecule.</p>},
	keywords = {asymmetric dihydroxylation, baclofen, cyclic sulfate, gamma-aminobutyric acid, Parkinsons{\textquoteright} disease},
	issn = {0376-4699},
	author = {Thakur, V. V. and Paraskar, A. S. and Sudalai, A.}
}
