@article { ISI:000243735500042,
	title = {Facile chemo-, regio-, and diastereoselective approach to cis-3,5-disubstituted gamma-butyrolactones and fused gamma-butyrolactones},
	journal = {Journal of Organic Chemistry},
	volume = {72},
	number = {3},
	year = {2007},
	month = {FEB},
	pages = {1009-1012},
	publisher = {AMER CHEMICAL SOC},
	type = {Article},
	address = {1155 16TH ST, NW, WASHINGTON, DC 20036 USA},
	abstract = {<p>Chemoselective S(N)2{\textquoteright} condensation of primary enolates of alkyl methyl ketones 2a-e with dimethyl bromomethylfumarate ( 1) followed by highly diastereoselective NaBH4 reduction of the ketone function in the formed ketodiesters 3a-e and the regioselective in situ lactonization of the unisolable intermediates 4a-e exclusively furnished the cis-3,5-disubstituted gamma-butyrolactones (+/-)-5a-e in very good yields. Similarly, the face-selective coupling reaction of cyclohexanone enolate with 1 to form a mixture of diastereomers in an 8: 2 ratio followed by a highly selective reductive cyclization of 9 plus 10 exclusively provided the cis-octahydrobenzofuran (+/-)- 12 in 70\% overall yield.</p>},
	issn = {0022-3263},
	doi = {10.1021/jo0619128},
	author = {Baag, Md. Merajuddin and Puranik, Vedavati G. and N. P. Argade}
}
