@article { ISI:000373993600011,
	title = {Facile synthesis of new N-sulfonamidyl-4-thiazolidinone derivatives and their biological evaluation},
	journal = {New Journal of Chemistry},
	volume = {40},
	number = {4},
	year = {2016},
	month = {FEB},
	pages = {3047-3058},
	publisher = {ROYAL SOC CHEMISTRY},
	address = {THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND},
	abstract = {<p>The one-pot three-component syntheses of new N-sulfonamide-thiazolidin-4-one derivatives were carried out in excellent yield using [HDBU][HSO4] as an ionic liquid under solvent-free conditions. The newly synthesized compounds were screened against fungal strains and a number of compounds were seen to display excellent antifungal activity. In addition, the synthesized compounds were screened for their scavenging activity of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and showed very good antioxidant activity. Finally, theoretical predictions derived from molecular docking studies against the potential target sterol 14 alpha-demethylase (CYP51) helped establish a link between the observed biological activity and the binding affinity, thereby providing insights into the specific bonding and non-bonding interactions governing the activity.</p>},
	issn = {1144-0546},
	doi = {10.1039/c6nj00021e},
	author = {Subhedar, Dnyaneshwar D. and Shaikh, Mubarak H. and Khan, Firoz A. Kalam and Sangshetti, Jaiprakash N. and Khedkar, Vijay M. and Shingate, Bapurao B.}
}
