@article { ISI:000237405000023,
	title = {Co-catalyzed reductive cyclization of azido and cyano substituted alpha,beta-unsaturated esters with NaBH4: enantioselective synthesis of (R)-baclofen and (R)-rolipram},
	journal = {Tetrahedron},
	volume = {62},
	number = {20},
	year = {2006},
	month = {MAY},
	pages = {4907-4916},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	type = {Article},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>Sodium borohydride in combination with a catalytic amount of CoCl, has been found to be an excellent catalytic system in reductive cyclizations of suitably substituted azido and cyano groups of alpha,beta-unsaturated esters to afford gamma and delta-lactams in high yields. The process has been demonstrated for the enantioselective synthesis of (R)-baclofen, (R)-rolipram, and (R)-4-fluorophenylpiperidinone, a key intermediate for (-)-paroxetine. (c) 2006 Elsevier Ltd. All rights reserved.</p>},
	keywords = {Asymmetric synthesis, cobalt chloride, gamma and delta-lactams, reduction, sodium borohydride},
	issn = {0040-4020},
	doi = {10.1016/j.tet.2006.03.017},
	author = {Paraskar, A. S. and Sudalai, A.}
}
