@article { ISI:000237485300010,
	title = {Ligand-, copper-, and amine-free one-pot synthesis of 2-substituted indoles via Sonogashira coupling 5-endo-dig cyclization},
	journal = {Tetrahedron},
	volume = {62},
	number = {21},
	year = {2006},
	month = {MAY},
	pages = {5109-5115},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	type = {Article},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>Results of the optimized conditions for the one-pot synthesis of 2-substituted indoles via palladium acetate catalyzed tandem Sonogashira coupling 5-endo-dig cyclization at room temperature under ultrasonic irradiation and standard stirred conditions are described. Electron-donating and electron-withdrawing groups present in both Coupling partners were well tolerated under these mild conditions. A copper-, ligand- and amine-free condition is an important feature of this protocol. Significant enhancement of reaction rates was observed for the reactions employing ultrasonic irradiation. (c) 2006 Elsevier Ltd. All rights reserved.</p>},
	keywords = {5-endo-dig cyclization, Indole, synthesis, Ultrasound},
	issn = {0040-4020},
	doi = {10.1016/j.tet.2006.03.035},
	author = {Palimkar, Sanjay S. and Kumar, P. Harish and Lahoti, Rajgopal J. and Srinivasan, Kumar V.}
}
