@article { ISI:000277404300005,
	title = {Interaction between ataxin-2 binding protein 1 and cubitus-interruptus during wing development in drosophila},
	journal = {Developmental Biology},
	volume = {341},
	number = {2},
	year = {2010},
	month = {MAY},
	pages = {389-399},
	publisher = {ACADEMIC PRESS INC ELSEVIER SCIENCE},
	address = {525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA},
	abstract = {<p>Animal growth and development is dependent on reiterative use of key signaling pathways such as Hedgehog (Hh) pathway. It is widely believed that Cubitus-interruptus (Ci) mediates all functions of Hh pathway. Here we report that CG32062, the Drosophila homologue of Ataxin-2 Binding Protein 1 (dA2BP1), functions as a cofactor of Ci to specify intervein region between L3 and L4 veins of the adult wing. Specifically, Ci-mediated transactivation of knot/collier (kn) in this region of the developing wing imaginal disc is dependent on dA2BP1 function. Protein interaction studies and chromatin-immunoprecipiation experiments suggest that Ci helps dA2BP1 to bind kn promoter, which in turn may help Ci to activate kn expression. These results suggest a mechanism by which Ci may activate targets such as kn, which do not have classical Ci/Gli-binding sites. (C) 2010 Elsevier Inc. All rights reserved.</p>},
	keywords = {CG32062, Collier, Hedgehog, Knot, SCA2},
	issn = {0012-1606},
	doi = {10.1016/j.ydbio.2010.02.039},
	author = {Usha, N. and Shashidhara, L. S.}
}
