@article { ISI:000290297800015,
	title = {First total synthesis of 5-hydroxy-3-methyl-4-propylsulfanyl-5H-furan-2-one: a cancer chemopreventive agent},
	journal = {Synthesis-Stuttgart},
	number = {10},
	year = {2011},
	month = {MAY},
	pages = {1595-1598},
	publisher = {GEORG THIEME VERLAG KG},
	address = {RUDIGERSTR 14, D-70469 STUTTGART, GERMANY},
	abstract = {<p>The first total synthesis of 5-hydroxy-3-methyl-4-propylsulfanyl-5H-furan-2-one, a newly discovered natural product with anticancer property is described by two different routes. A sequence involving an incorporation of a methyl group via a Gilman reagent and a chemoselective reduction of a cyclic anhydride functionality are the key steps. The methods proposed start from easily available starting materials and allow ready preparation of the final compound in good overall yield.</p>},
	keywords = {Allium cepa, chemopreventive, Gilman reagent, selective, synthesis},
	issn = {0039-7881},
	doi = {10.1055/s-0030-1260004},
	author = {Borikar, Sanjay P. and Paul, Vincent and Puranik, Vedavati G. and Sathe, Vilas T. and Lagunas-Rivera, Selene and Ordonez, Mario}
}
